ArticleGenetics1991
Sequence identity in an early chorion multigene family is the result of localized gene conversion.
Article in Genetics, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 49 citations in OpenAlex.
- The Widespread Prevalence and Functional Significance of Silk-Like Structural Proteins in Metazoan Biological Materials.PloS one · 2016Article
- Proteomics reveals novel components of the Anopheles gambiae eggshell.Journal of insect physiology · 2010Article
- Evolution of repeated sequences in the ribosomal DNA intergenic spacer of 32 arthropod species.Journal of molecular evolution · 2010Article
- Controlled chaos of polymorphic mucins in a metazoan parasite (Schistosoma mansoni) interacting with its invertebrate host (Biomphalaria glabrata).PLoS neglected tropical diseases · 2008Article
- Evolutionary history and mode of the amylase multigene family in Drosophila.Journal of molecular evolution · 2003Article
- Concerted evolution: molecular mechanism and biological implications.American journal of human genetics · 1999Review
- Extraordinary ribosomal spacer length heterogeneity in a neotyphodium endophyte hybrid: implications for concerted evolution.Genetics · 1998Article
- A cluster of cuticle protein genes of Drosophila melanogaster at 65A: sequence, structure and evolution.Genetics · 1997Article
- Concerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion.The EMBO journal · 1997Article
- Ribosomal DNA evolution at the population level: nucleotide variation in intergenic spacer arrays of Daphnia pulex.Genetics · 1995Article
- Sequence analysis of a small early chorion gene subfamily interspersed within the late gene locus in Bombyx mori.Journal of molecular evolution · 1995Article
- Article
- Evolution of chorion gene families in lepidoptera: characterization of 15 cDNAs from the gypsy moth.Journal of molecular evolution · 1994Article
- Silk moth chorion pseudogenes: hallmarks of genomic evolution by sequence duplication and gene conversion.Journal of molecular evolution · 1993Article
- Pao, a highly divergent retrotransposable element from Bombyx mori containing long terminal repeats with tandem copies of the putative R region.Nucleic acids research · 1993Article
- The evolutionary relationship of avian and mammalian myosin heavy-chain genes.Journal of molecular evolution · 1993Article
- Simulation study of a multigene family, with special reference to the evolution of compensatory advantageous mutations.Genetics · 1992Article
- New nucleotide sequence data on the EMBL File Server.Nucleic acids research · 1992Article
- The possible evolutionary significance of repeat elements near and within an early chorion gene in the late chorion locus of Bombyx mori.Journal of molecular evolution · 1992Article
- Three copies of the early gene 6F6 are interspersed in and around the late chorion gene cluster of Bombyx mori.Journal of molecular evolution · 1992Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The multigene families that encode the chorion (eggshell) of the silk moth, Bombyx mori, are closely linked on one chromosome. We report here the isolation and characterization of two segments, totaling 102 kb of genomic DNA, containing the genes expressed during the early period of choriogenesis. Most of these early genes can be divided into two multigene families, ErA and ErB, organized into five divergently transcribed ErA/ErB gene pairs. Nucleotide sequence identity in the major coding regions of the ErA genes was 96%, while nucleotide sequence identity for the ErB major coding regions was only 63%. Selection pressure on the encoded proteins cannot explain this difference in the level of sequence conservation between the ErA and ErB gene families, since when only fourfold redundant codon positions are considered, the divergence within the ErA genes is 8%, while the divergence within the ErB genes (corrected for multiple substitutions at the same site) is 110%. The high sequence identity of the ErA major exons can be explained by sequence exchange events similar to gene conversion localized to the major exon of the ErA genes. These gene conversions are correlated with the presence of clustered copies of the nucleotide sequence GGXGGX, encoding paired glycine residues. This sequence has previously been correlated with gradients of gene conversion that extend throughout the coding and noncoding regions of the High-cysteine (Hc) chorion genes of B. mori. We suggest that the difference in the extent of the conversion tracts in these gene families reflects a tendency for these recombination events to become localized over time to the protein encoding regions of the major exons.
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