Evidence map›Paper›PMID 18728850›Full record

ArticleTherapeutics and clinical risk management2008

Treating psoriasis with adalimumab.

Eihab A Alwawi, Stephanie L Mehlis, Kenneth B Gordon

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Unveiling Psoriasis: Delving into Pathogenesis, Treatment Breakthroughs, and Patent Trends.Recent advances in inflammation & allergy drug discovery · 2025
    Review
  8. Article
  9. Inflammation and Psoriasis: A Comprehensive Review.International journal of molecular sciences · 2023
    Review
  10. Review
  11. Potential Therapeutic Value of the STING Inhibitors.Molecules (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Review
  14. Observational
  15. New Treatment Addressing the Pathogenesis of Psoriasis.International journal of molecular sciences · 2020
    Review
  16. Review
  17. Article
  18. Article
  19. Biologics in dermatologic therapy - an update.Indian journal of dermatology · 2009
    Article
  20. Biologics and Biosimilars in Psoriasis.Indian journal of dermatology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eihab A AlwawiDivision of Dermatology and Department of Medicine, Evanston Northwestern Healthcare Skokie, IL, USA.
Stephanie L Mehlis
Kenneth B Gordon
Northwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a common, chronic, inflammatory skin disease that can have a significant impact on the quality of life of those who are afflicted. Recent advances in the understanding of the pathophysiology of psoriasis have led to the development of new, genetically engineered, targeted therapies for this disease. Among the most successful strategies for treatment has been the use of biologic immunotherapies targeting tumor necrosis factor alpha (TNF). Recent research has evaluated the efficacy and safety of a new anti-TNF agent, adalimumab. Adalimumab is a human monoclonal antibody that is approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) for the treatment of rheumatoid arthritis and psoriatic arthritis. Recently released data from large, randomized clinical trials suggests that adalimumab has significant efficacy for the treatment of chronic plaque psoriasis and is well tolerated. Thus, adalimumab seems to be a promising therapeutic approach for patients who suffer from moderate to severe plaque psoriasis.

Indexed as

adalimumabpsoriasistumor necrosis factor alpha

Identifiers

PMID18728850
PMCPMC2504074
OpenAlexW2171992169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.