ArticleNeuropsychiatric disease and treatment2008
Differential diagnoses and management strategies in patients with schizophrenia and bipolar disorder.
Article in Neuropsychiatric disease and treatment, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- At risk for schizophrenic or affective psychoses? A meta-analysis of DSM/ICD diagnostic outcomes in individuals at high clinical risk.Schizophrenia bulletin · 2013Pooled it
- Factors associated with the frequency of manic and depressive episodes in bipolar disorder: a multicenter study in China.BMC psychiatry · 2025Article
- E-Screening for Prenatal Depression in Kampala, Uganda Using the Edinburgh Postnatal Depression Scale: Survey Results.Online journal of public health informatics · 2025Article
- Are There Any Differences in Clinical and Biochemical Variables between Bipolar Patients with or without Lifetime Psychotic Symptoms?Journal of clinical medicine · 2023Article
- Correlates of long duration of untreated illness (DUI) in patients with bipolar disorder: results of an observational study.Annals of general psychiatry · 2023Article
- Misdiagnosis, detection rate, and associated factors of severe psychiatric disorders in specialized psychiatry centers in Ethiopia.Annals of general psychiatry · 2021Article
- Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction.Nature communications · 2019Article
- Classification of schizophrenia by intersubject correlation in functional connectome.Human brain mapping · 2019Article
- Analysis of Misdiagnosis of Bipolar Disorder in An Outpatient Setting.Shanghai archives of psychiatry · 2018Article
- Socio-demographic and clinical characterization of patients with Bipolar Disorder I vs II: a Nationwide Italian Study.European archives of psychiatry and clinical neuroscience · 2018Article
- A Bayesian Approach to Modeling Risk of Hospital Admissions Associated With Schizophrenia Accounting for Underdiagnosis of the Disorder in Administrative Records.Computational psychiatry (Cambridge, Mass.) · 2018Article
- Predictors of a Shorter Time to Hospitalization in Patients with Bipolar Disorder: Medication during the Acute and Maintenance Phases and Other Clinical Factors.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2017Article
- An epidemiologic and clinical overview of medical and psychopathological comorbidities in major psychoses.European archives of psychiatry and clinical neuroscience · 2011Article
Corrections and comments
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Authors and funding
2 authors.
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Abstract
Successful treatment of psychiatric disorders, including bipolar disorder and schizophrenia, is complicated and is affected by a broad range of factors associated with the diagnosis, choice of treatment and social factors. In these patients, treatment management must focus on accurate and early diagnosis, to ensure that correct treatment is administered as soon as possible. In both disorders, the treatment of the disease in the acute phase must be maintained long term to provide continuous relief and normal function; the treatment choice in the early stages of the disease may impact on long-term outcomes. In schizophrenia, treatment non-compliance is an important issue, with up to 50% of patients discontinuing treatment for reasons as diverse as efficacy failure, social barriers, and more commonly, adverse events. Treatment non-compliance also remains an issue in bipolar disorder, as tolerability of mood stabilizers, especially lithium, is not always good, and combination treatments are frequent. In order to achieve an optimal outcome in which the patient continues with their medication life-long, treatment should be tailored to each individual, taking into account treatment and family history, and balancing efficacy with tolerability to maximize patient benefit and minimize the risk of discontinuation. These case studies illustrate how treatment should be monitored, tailored and often changed over time to meet these needs.
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