Evidence map›Paper›PMID 18728765›Full record

ArticleMarine drugs2008

Diverse bacterial PKS sequences derived from okadaic acid-producing dinoflagellates.

Roberto Perez, Li Liu, Jose Lopez, Tianying An, Kathleen S Rein

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Epoxide-opening cascades in the synthesis of polycyclic polyether natural products.Angewandte Chemie (International ed. in English) · 2009
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Roberto PerezDepartment of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA. rperez@med.miami.edu
Li Liu
Jose Lopez
Tianying An
Kathleen S Rein
Florida International University · US

Funding

Pilot--Molecular Monitoring of Toxic DinoflagellatesS11ES011181 · NIEHS · FLORIDA INTERNATIONAL UNIVERSITY · PI REIN, KATHLEEN S · 2001 to 2011
$6.9M
Toxic Harmful Algal Blooms (HABs)P50ES012736 · NIEHS · UNIVERSITY OF MIAMI ROSENTEIL SCHOOL · PI FLEMING, LORA ELDERKIN · 2004 to 2010
$2.7M
NIEHS NIH HHS P50 ES012736NIEHS NIH HHS P50 ES12736-01NIEHS NIH HHS S11 ES011181NIEHS NIH HHS S11 ES11181
6 · The paper itself

Abstract

Okadaic acid (OA) and the related dinophysistoxins are isolated from dinoflagellates of the genus Prorocentrum and Dinophysis. Bacteria of the Roseobacter group have been associated with okadaic acid producing dinoflagellates and have been previously implicated in OA production. Analysis of 16S rRNA libraries reveals that Roseobacter are the most abundant bacteria associated with OA producing dinoflagellates of the genus Prorocentrum and are not found in association with non-toxic dinoflagellates. While some polyketide synthase (PKS) genes form a highly supported Prorocentrum clade, most appear to be bacterial, but unrelated to Roseobacter or Alpha-Proteobacterial PKSs or those derived from other Alveolates Karenia brevis or Crytosporidium parvum.

Indexed as

Amino Acid SequenceAnimalsBase SequenceDinoflagellidaOkadaic AcidPhylogenyPolyketide SynthasesRNA, Ribosomal, 16SRoseobacterSequence AlignmentOkadaic AcidPolyketide SynthasesRNA, Ribosomal, 16Sbiosynthesisokadaic acidpolyketidepolyketide synthaseRoseobacter

Identifiers

PMID18728765
PMCPMC2525486
OpenAlexW2149166752

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.