ArticleNeuropsychiatric disease and treatment2008
Epilepsy and suicide: pathogenesis, risk factors, and prevention.
Article in Neuropsychiatric disease and treatment, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- A Meta-Analysis of the Rates of Suicide Ideation, Attempts and Deaths in People with Epilepsy.International journal of environmental research and public health · 2019Pooled it
- Prevalence and factors associated with suicidality among adolescents with epilepsy attending national referral hospitals in Uganda.Discover mental health · 2026Article
- A quantitative and T-pattern analysis of anxiety-like behavior in male GAERS, NEC, and Wistar rats bred under the same conditions, against a commercially available Wistar control group in the hole board and elevated plus maze tests.CNS neuroscience & therapeutics · 2024Article
- I would be better off dead: investigating suicidal ideation in people with epilepsy.Arquivos de neuro-psiquiatria · 2022Article
- Depressive symptoms in patients with epilepsy and clinically associated features in a single tertiary center.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Suicidality in Epilepsy: Does It Share Common Pathogenic Mechanisms with Epilepsy?Current topics in behavioral neurosciences · 2022Observational
- Astrocytes and Glutamine Synthetase in Epileptogenesis.Journal of neuroscience research · 2019Review
- Hospital care for mental health and substance abuse in children with epilepsy.Epilepsy & behavior : E&B · 2016Article
- Inhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy.Epilepsy & behavior : E&B · 2015Article
- Suicidality and Its Risk Factors in Korean People with Epilepsy: A MEPSY Study.Journal of clinical neurology (Seoul, Korea) · 2015Article
- Depression in epilepsy: a critical review from a clinical perspective.Nature reviews. Neurology · 2011Review
- An update on antiepileptic drugs and suicide: are there definitive answers yet?Epilepsy currents · 2010Article
- Predictors of suicidal ideation in people with epilepsy living in Korea.Journal of clinical neurology (Seoul, Korea) · 2010Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression and suicide tendencies are common in chronic diseases, especially in epilepsy and diabetes. Suicide is one of the most important causes of death, and is usually underestimated. We have analyzed several studies that compare mortality as a result of suicide in epileptic patients and in the general population. All the studies show that epileptic patients have a stronger tendency toward suicide than healthy controls. Moreover it seems that some kinds of epilepsy have a higher risk for suicide (temporal-lobe epilepsy). Among the risk factors are surgery therapy (suicide tendency five times higher than patients in pharmacological therapy), absence of seizures for a long time, especially after being very frequent, and psychiatric comorbidity (major depression, anxiety-depression disorders, personality disorders, substance abuse, psychoses). The aim of the review was to analyze the relationship between suicide and epilepsy, to identify the major risk factors, and to analyze effective treatment options.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.