Trial reportEuropean journal of applied physiology2008
Plantar flexion: an effective training for peripheral arterial disease.
Trial report in European journal of applied physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 7 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Effect of supervised exercise training on cardiovascular function in patients with intermittent claudication: a systematic review and meta-analysis of randomized controlled trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Pooled it
- Intensity-dependent effects of exercise therapy on walking performance and aerobic fitness in symptomatic patients with lower-extremity peripheral artery disease: A systematic review and meta-analysis.Vascular medicine (London, England) · 2022Pooled it
- Pooled it
- Modes of exercise training for intermittent claudication.The Cochrane database of systematic reviews · 2020Pooled it
- Exercise for intermittent claudication.The Cochrane database of systematic reviews · 2017Pooled it
- Exercise training for management of peripheral arterial disease: a systematic review and meta-analysis.Sports medicine (Auckland, N.Z.) · 2015Pooled it
- The effect of exercise on fitness and performance-based tests of function in intermittent claudication: a systematic review.Sports medicine (Auckland, N.Z.) · 2013Pooled it
- Prediction of upper extremity peak oxygen consumption from heart rate during submaximal arm cycling in young and middle-aged adults.European journal of applied physiology · 2019Article
- Alternative Statistical Analysis Shows Exercise Training-Induced Improvements in Peak VO2 are Clinically Significant.Sports medicine (Auckland, N.Z.) · 2015Article
- Evaluation of 6- and 12-month supervised exercise training on strength and endurance parameters in patients with peripheral arterial disease.Wiener klinische Wochenschrift · 2014Article
- Exercise-training-induced changes in metabolic capacity with age: the role of central cardiovascular plasticity.Age (Dordrecht, Netherlands) · 2014Article
- Exercise therapy for claudication: latest advances.Current treatment options in cardiovascular medicine · 2013Article
- Plantar flexion training primes peripheral arterial disease patients for improvements in cardiac function.European journal of applied physiology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examined whether a training intervention likely to elicit adaptations in the leg could result in reduced leg pain and increased whole body physical capacity. Twenty-seven peripheral arterial disease (PAD) patients were randomized to either an individual leg plantar flexion training group (TG) training 4 x 4 min intervals at 80% of maximal work rate three times per week for 8 weeks or a control group. The TG significantly increased plantar flexion peak oxygen uptake and power output by 23.5 and 43.9%, respectively. Treadmill peak oxygen uptake (VO(2peak)) significantly increased 12.3% in the TG and was associated with a significant increased time to exhaustion of 20.0% when treadmill walking. Eleven of 14 patients no longer reported leg pain limitations at VO(2peak). No differences in cardiac output measured at VO(2peak), or walking economy were observed. Plantar flexion training was effective in increasing VO(2peak) and walking performance, and may be a useful strategy in treatment of PAD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.