Evidence map›Paper›PMID 18725798›Full record

ReviewCurrent opinion in infectious diseases2008

New insights into Entamoeba histolytica pathogenesis.

Leigh A Baxt, Upinder Singh

Abstract readReview
In one paragraph

Review in Current opinion in infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Gal/GalNac lectin as a possible acetylcholine receptor inFrontiers in cellular and infection microbiology · 2023
    Article
  5. Article
  6. The Role of Acetate Kinase in the Human ParasiteParasitologia (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Encystation ofMicroorganisms · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Leptin Functions in Infectious Diseases.Frontiers in immunology · 2018
    Review
  13. In Vitro Testing of PotentialThe American journal of tropical medicine and hygiene · 2017
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Leptin and mucosal immunity.Mucosal immunology · 2012
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Leigh A BaxtDepartment of Microbiology and Immunology, Stanford University, Stanford, California, USA.
Upinder Singh

Funding

MOLECULAR BASIS OF HOST-PARASITE INTERACTIONT32AI007328 · NIAID · STANFORD UNIVERSITY · PI JUSTIN L SONNENBURG · 1987 to 2026
$11.9M
Investigating Entamoeba histolytica Colonic PathogenesisR01AI053724 · NIAID · STANFORD UNIVERSITY · PI SINGH, UPINDER · 2003 to 2012
$3.8M
NIAID NIH HHS R01 AI053724NIAID NIH HHS T32 AI007328
6 · The paper itself

Abstract

purpose of reviewEntamoeba histolytica is an important global pathogen and a leading cause of parasitic death worldwide. This article summarizes significant research findings over the last year. RECENT

findingsEfforts have focused primarily on identification of novel virulence determinants in E. histolytica, transcriptional profiling during tissue invasion and stage conversion, and characterization of basic cell biological processes. Additionally, new techniques for gene silencing have been identified. SUMMARY: A comprehensive examination of the parasite lifestyle on a whole genome level has been undertaken, allowing identification of new virulence genes and signaling pathways and processes relevant to amebic biology.

Indexed as

Genome, ProtozoanAnimalsDNA, ProtozoanEntamoeba histolyticaEntamoebiasisGene Expression ProfilingGenes, ProtozoanOligonucleotide Array Sequence AnalysisProtozoan ProteinsRetroelementsVirulenceDNA, ProtozoanProtozoan ProteinsRetroelements

Identifiers

PMID18725798
PMCPMC2688559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.