ReviewCurrent opinion in biotechnology2008
Gene module level analysis: identification to networks and dynamics.
Review in Current opinion in biotechnology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed.
- Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation.PloS one · 2013Trial
- BADDADAN: Mechanistic modelling of time-series gene module expression.Quantitative plant biology · 2025Article
- PONYTA: prioritization of phenotype-related genes from mouse KO events using PU learning on a biological network.Bioinformatics (Oxford, England) · 2024Article
- Article
- Integrated bioinformatic analyses investigate macrophage-M1-related biomarkers and tuberculosis therapeutic drugs.Frontiers in genetics · 2023Article
- ccTCM: A quantitative component and compound platform for promoting the research of traditional Chinese medicine.Computational and structural biotechnology journal · 2023Article
- Identification of disease-related genes and construction of a gene co-expression database in non-alcoholic fatty liver disease.Frontiers in genetics · 2023Article
- Inference of epigenetic subnetworks by Bayesian regression with the incorporation of prior information.Scientific reports · 2022Article
- No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing.Translational psychiatry · 2021Article
- The role of gene to gene interaction in the breast's genomic signature of pregnancy.Scientific reports · 2021Article
- The functional study of human proteins using humanized yeast.Journal of microbiology (Seoul, Korea) · 2020Review
- Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers.Acta neuropathologica communications · 2019Article
- It is time to apply biclustering: a comprehensive review of biclustering applications in biological and biomedical data.Briefings in bioinformatics · 2019Review
- Exploring the genetic basis of gene transcript abundance and metabolite levels in loblolly pine (Pinus taeda L.) using association mapping and network construction.BMC genetics · 2018Article
- Identification and replication of RNA-Seq gene network modules associated with depression severity.Translational psychiatry · 2018Article
- Article
- SMARCE1 is required for the invasive progression of in situ cancers.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Entropy-based divergent and convergent modular pattern reveals additive and synergistic anticerebral ischemia mechanisms.Experimental biology and medicine (Maywood, N.J.) · 2016Article
- A new strategy for exploring the hierarchical structure of cancers by adaptively partitioning functional modules from gene expression network.Scientific reports · 2016Article
- Reconstruction of gene regulatory modules from RNA silencing of IFN-α modulators: experimental set-up and inference method.BMC genomics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Nature exhibits modular design in biological systems. Gene module level analysis is based on this module concept, aiming to understand biological network design and systems behavior in disease and development by emphasizing on modules of genes rather than individual genes. Module level analysis has been extensively applied in genome wide level analysis, exploring the organization of biological systems from identifying modules to reconstructing module networks and analyzing module dynamics. Such module level perspective provides a high level representation of the regulatory scenario and design of biological systems, promising to revolutionize our view of systems biology, genetic engineering as well as disease mechanisms and molecular medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.