ReviewNeuropharmacology2009
Bidirectional translational research: Progress in understanding addictive diseases.
Review in Neuropharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Clonidine Maintenance Prolongs Opioid Abstinence and Decouples Stress From Craving in Daily Life: A Randomized Controlled Trial With Ecological Momentary Assessment.The American journal of psychiatry · 2015Trial
- Genetic variants associated with post-traumatic stress symptoms in patients with gynecologic cancer.Gynecologic oncology · 2023Article
- Adenosine Monophosphate-activated Protein Kinase (AMPK) in serotonin neurons mediates select behaviors during protracted withdrawal from morphine in mice.Behavioural brain research · 2022Article
- Enhanced anxiety in the male offspring of sires that self-administered cocaine.Addiction biology · 2016Article
- Next generation effects of female adolescent morphine exposure: sex-specific alterations in response to acute morphine emerge before puberty.Behavioural pharmacology · 2014Article
- Article
- Tolerance and sensitization to chronic escalating dose heroin following extended withdrawal in Fischer rats: possible role of mu-opioid receptors.Psychopharmacology · 2013Article
- Translational health research: perspectives from health education specialists.Clinical and translational medicine · 2012Article
- OPRM1 and diagnosis-related posttraumatic stress disorder in binge-drinking patients living with HIV.AIDS and behavior · 2012Article
- Dose escalation and dose preference in extended-access heroin self-administration in Lewis and Fischer rats.Psychopharmacology · 2012Article
- Measuring the incentive value of escalating doses of heroin in heroin-dependent Fischer rats during acute spontaneous withdrawal.Psychopharmacology · 2012Article
- Mass spectrometry-based neuropeptidomics of secretory vesicles from human adrenal medullary pheochromocytoma reveals novel peptide products of prohormone processing.Journal of proteome research · 2010Article
- Dose preference and dose escalation in extended-access cocaine self-administration in Fischer and Lewis rats.Psychopharmacology · 2010Article
- Pharmacotherapy in the treatment of addiction: methadone.Journal of addictive diseases · 2010Article
- The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors.Brain research · 2010Review
- Effects of galanin on monoaminergic systems and HPA axis: Potential mechanisms underlying the effects of galanin on addiction- and stress-related behaviors.Brain research · 2010Review
- Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases.Brain research · 2010Review
- Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.Annals of the New York Academy of Sciences · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The focus of this review is primarily on recent developments in bidirectional translational research on the addictions, within the Laboratory of the Biology of Addictive Diseases at The Rockefeller University. This review is subdivided into major interacting aspects, including (a) Investigation of neurobiological and molecular adaptations (e.g., in genes for the opioid receptors or endogenous neuropeptides) in response to cocaine or opiates, administered under laboratory conditions modeling chronic patterns of human self-exposure (e.g., chronic escalating "binge"). (b) The impact of such drug exposure on the hypothalamic-pituitary-adrenal (HPA) axis and interacting neuropeptidergic systems (e.g., opioid, orexin and vasopressin). (c) Molecular genetic association studies using candidate gene and whole genome approaches, to define particular systems involved in vulnerability to develop specific addictions, and response to pharmacotherapy. (d) Neuroendocrine challenge studies in normal volunteers and current addictive disease patients along with former addicts in treatment, to investigate differential pharmacodynamics and responsiveness of molecular targets, in particular those also investigated in the experimental and molecular genetic approaches as described above.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.