Trial reportGastroenterology2008
Impact of wide-angle, high-definition endoscopy in the diagnosis of colorectal neoplasia: a randomized controlled trial.
Trial report in Gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 102 citations in OpenAlex.
- Trial
- Adenoma detection at colonoscopy by polypectomy in withdrawal only versus both insertion and withdrawal: a randomized controlled trial.Surgical endoscopy · 2015Trial
- Short turn radius colonoscope in an anatomical model: retroflexed withdrawal and detection of hidden polyps.World journal of gastroenterology · 2015Trial
- Evaluation of the cecal withdrawal vocal timer in screening colonoscopies for optimizing withdrawal time and adenoma detection rate.Therapeutic advances in gastroenterology · 2025Article
- Article
- Factors Associated with Polyp Detection Rate in European Colonoscopy Practice: Findings of The European Colonoscopy Quality Investigation (ECQI) Group.International journal of environmental research and public health · 2022Article
- Diagnostic Ability of High-definition Imaging Using Ultraslim Endoscopes in Early Gastric Cancer.Journal of gastric cancer · 2021Article
- Comparison of the detection of colorectal lesions in different endoscopic modalities: A network meta-analysis and systematic review.Experimental and therapeutic medicine · 2019Article
- Miniaturized omnidirectional flexible side-view endoscope for rapid monitoring of thin tubular biostructures.Biomedical optics express · 2019Article
- Improvement of arthroscopic surgical performance using a new wide-angle arthroscope in the surgical training.PloS one · 2019Article
- Is there a difference in adenoma detection rates between gastroenterologists and surgeons?World journal of gastrointestinal endoscopy · 2018Article
- The use of high definition colonoscopy versus standard definition: does it affect polyp detection rate?Surgical endoscopy · 2018Article
- Can technology increase adenoma detection rate?Therapeutic advances in gastroenterology · 2018Review
- The Dimensionless Squared Jerk: An Objective Parameter That Improves Assessment of Hand Motion Analysis during Simulated Shoulder Arthroscopy.BioMed research international · 2018Article
- A guide to multimodal endoscopy imaging for gastrointestinal malignancy - an early indicator.Nature reviews. Gastroenterology & hepatology · 2017Review
- High-definition colonoscopy increases adenoma detection rate.Surgical endoscopy · 2017Article
- Review
- Can Technology Improve the Quality of Colonoscopy?Current gastroenterology reports · 2016Review
- A new wide-angle arthroscopic system: a comparative study with a conventional 30° arthroscopic system.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016Article
- Feasibility of full-spectrum endoscopy: Korea's first full-spectrum endoscopy colonoscopic trial.World journal of gastroenterology · 2016Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
aimsIt is essential to optimize standard colonoscopy technique to be able to increase polyp detection. We sought to compare the performance of colonoscopy using a high-definition, wide-angle endoscope (HDE) versus a standard colonoscope (SC) for the detection of colorectal neoplasia. PATIENTS AND
methodsAll consecutive consenting adult patients referred from primary care centers were included and randomly assigned at a 1:1 ratio to undergo HDE or SC. Times to reach and withdraw from the cecum were measured. Morphology, size, location, and pathologic diagnosis of each polyp were recorded. Sample size calculation resulted in a total of 682 patients needed.
resultsA total of 693 consecutive patients fulfilled all inclusion criteria (73 excluded owing to insufficient bowel preparation). Each arm included 310 patients with no baseline characteristic differences. Time to reach the cecum was slightly superior for SC (8.9 +/- 4.8 minutes vs 8.2 +/- 4.5 minutes; P = .055). Pathology examination was feasible in 418 lesions (272 adenomas, 109 hyperplastic polyps, and 37 inflammatory lesions). Both techniques detected a similar number and type of lesions, and there were no differences in the distribution along the colon, in the degree of dysplasia, or morphology of adenomas. The per-patient basis analyses demonstrated that there were no differences between the 2 arms of the study in the detection rates of polyps (SC, 0.84 +/- 1.59; HDE, 0.83 +/- 1.30), adenomas (0.45 +/- 1.07 vs 0.43 +/- 0.87), small adenomas (0.22 +/- 0.71 vs 0.28 +/- 0.78), flat adenomas (0.30 +/- 0.91 vs 0.21 +/- 0.63), or hyperplastic polyps (0.16 +/- 0.50 vs 0.18 +/- 0.54).
conclusionHDE did not detect significantly more colorectal neoplasia than SC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.