ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2008
Relationship of pneumocystis antibody response to severity of chronic obstructive pulmonary disease.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00869544 (Pneumocystis in Pathogenesis of HIV-associated Emphysema), which is not on this map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pneumocystis in Pathogenesis of HIV-associated Emphysema
Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Experimental Pneumocystis infection in dexamethasone immunosuppressed macaques.Medical mycology · 2025Article
- Pneumocystis Jirovecii Pneumonia in Two Immunosuppressed Non-HIV Infected Patients: A Clinical and Therapeutic Analysis.Infection and drug resistance · 2025Article
- Protective efficacy of a 'pan-fungal' vaccination strategy against experimentalFrontiers in immunology · 2025Article
- Immunogenicity and protective efficacy of a pan-fungal vaccine in preclinical models of aspergillosis, candidiasis, and pneumocystosis.PNAS nexus · 2022Article
- Demographic and Socioeconomic Factors Associated with Fungal Infection Risk, United States, 2019.Emerging infectious diseases · 2022Review
- Prevalence and Healthcare Burden of Fungal Infections in the United States, 2018.Open forum infectious diseases · 2022Article
- A therapeutic vaccine strategy to preventFrontiers in immunology · 2022Article
- Relationship ofBMJ open respiratory research · 2021Article
- Review
- Article
- Immunization withHuman vaccines & immunotherapeutics · 2019Article
- Pathogenic Fungal Infection in the Lung.Frontiers in immunology · 2019Review
- Pneumocystis infection alters the activation state of pulmonary macrophages.Immunobiology · 2017Article
- Vaccine-Induced Immunogenicity and Protection Against Pneumocystis Pneumonia in a Nonhuman Primate Model of HIV and Pneumocystis Coinfection.The Journal of infectious diseases · 2016Article
- Pneumocystis jirovecii can be productively cultured in differentiated CuFi-8 airway cells.mBio · 2014Article
- Trimethoprim-sulfamethoxazole treatment does not reverse obstructive pulmonary changes in pneumocystis-colonized nonhuman primates with SHIV infection.Journal of acquired immune deficiency syndromes (1999) · 2014Article
- Modulation of inflammasome-mediated pulmonary immune activation by type I IFNs protects bone marrow homeostasis during systemic responses to Pneumocystis lung infection.Journal of immunology (Baltimore, Md. : 1950) · 2013Article
- Colonization by Pneumocystis jirovecii and its role in disease.Clinical microbiology reviews · 2012Review
- Interactions between HIV infection and chronic obstructive pulmonary disease: Clinical and epidemiological aspects.Respiratory research · 2011Review
- Pneumocystis infection and the pathogenesis of chronic obstructive pulmonary disease.Immunologic research · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Pneumocystis colonization has been associated with severity of chronic obstructive pulmonary disease (COPD). The relationship of Pneumocystis antibody status to COPD severity has not been investigated, but antibody levels might relate to both colonization susceptibility and COPD progression. We investigated anti-Pneumocystis antibody titers and airway obstruction in a cohort of patients with COPD. Undetectable anti-Pneumocystis antibody titer was an independent predictor of more-severe airway obstruction, although use of inhaled corticosteroids is a possible confounder of this effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.