Evidence map›Paper›PMID 18722563›Full record

ReviewRespiratory physiology & neurobiology2008

Identification of neurotransmitters and co-localization of transmitters in brainstem respiratory neurons.

R L Stornetta

Abstract readReview
In one paragraph

Review in Respiratory physiology & neurobiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Molecular Organization of Autonomic, Respiratory, and Spinally-Projecting Neurons in the Mouse Ventrolateral Medulla.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  3. Article
  4. Article
  5. Diversity of reticulospinal systems in mammals.Current opinion in physiology · 2019
    Article
  6. Article
  7. Article
  8. Breathing matters.Nature reviews. Neuroscience · 2018
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Respiratory regulation in narcolepsy.Sleep & breathing = Schlaf & Atmung · 2012
    Article
  16. Article
  17. Overview: the neurochemistry of respiratory control.Respiratory physiology & neurobiology · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

R L StornettaDepartment of Pharmacology, University of Virginia Health System, P.O. Box 800735, 1300 Jefferson Park Avenue, Charlottesville, VA 22908, USA. rs3j@virginia.edu

Funding

Retrotrapezoid nucleus and central chemoreceptionR01HL074011 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GUYENET, PATRICE G. · 2003 to 2018
$6.6M
Organization of Central Sympathic PathwaysR01HL028785 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI STORNETTA, RUTH L · 1985 to 2020
$5.0M
ORGANIZATION OF CENTRAL SYMPATHETIC PATHWAYSR37HL028785 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GUYENET, PATRICE G. · 1999 to 2008
$3.0M
NHLBI NIH HHS HL28785NHLBI NIH HHS HL74011NHLBI NIH HHS R01 HL028785NHLBI NIH HHS R01 HL074011NHLBI NIH HHS R37 HL028785
6 · The paper itself

Abstract

Identifying the major ionotropic neurotransmitter in a respiratory neuron is of critical importance in determining how the neuron fits into the respiratory system, whether in producing or modifying respiratory drive and rhythm. There are now several groups of respiratory neurons whose major neurotransmitters have been identified and in some of these cases, more than one transmitter has been identified in particular neurons. This review will describe the physiologically identified neurons in major respiratory areas that have been phenotyped for major ionotropic transmitters as well as those where more than one transmitter has been identified. Although the purpose of the additional transmitter has not been elucidated for any of the respiratory neurons, some examples from other systems will be discussed.

Indexed as

AnimalsBrain StemHumansNerve Tissue ProteinsNeuronsNeurotransmitter AgentsRespiratory CenterRespiratory SystemNerve Tissue ProteinsNeurotransmitter Agents

Identifiers

PMID18722563
PMCPMC2642910

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.