Evidence map›Paper›PMID 18722380›Full record

ReviewJournal of molecular and cellular cardiology2008

Nitric oxide signaling and the regulation of myocardial function.

Mark T Ziolo, Mark J Kohr, Honglan Wang

Abstract readReview
In one paragraph

Review in Journal of molecular and cellular cardiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes.Journal of cardiovascular development and disease · 2018
    Review
  16. Article
  17. Article
  18. The Effects of Aqueous Extract fromEvidence-based complementary and alternative medicine : eCAM · 2017
    Article
  19. Cardioprotective Action ofFrontiers in pharmacology · 2017
    Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mark T ZioloDepartment of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA. ziolo.1@osu.edu
Mark J Kohr
Honglan Wang

Funding

NOS1/NOS3 Functional Effects on Cardiac Myocyte FunctionR01HL079283 · NHLBI · OHIO STATE UNIVERSITY · PI ZIOLO, MARK T · 2006 to 2010
$1.8M
Nitric oxide signaling in healthy and diseased cardiac myocytesK02HL094692 · NHLBI · OHIO STATE UNIVERSITY · PI ZIOLO, MARK T · 2009 to 2013
$521k
NHLBI NIH HHS K02 HL094692NHLBI NIH HHS R01 HL079283NHLBI NIH HHS R01HL079283
6 · The paper itself

Abstract

Nitric oxide, which is produced endogenously within cardiac myocytes by three distinct isoforms of nitric oxide synthase, is a key regulator of myocardial function. This review will focus on the regulation of myocardial function by each nitric oxide synthase isoform during health and disease, with a specific emphasis on the proposed end-targets and signaling pathways.

Indexed as

AnimalsCalcium-Binding ProteinsCyclic GMPHeartHumansModels, BiologicalMyocardial ContractionMyocardiumNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type INitric Oxide Synthase Type IIPhospholambanProtein IsoformsRyanodine Receptor Calcium Release ChannelSignal TransductionCalcium-Binding ProteinsCyclic GMPNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type INitric Oxide Synthase Type IINOS1 protein, humanNOS2 protein, humanPhospholambanProtein IsoformsRyanodine Receptor Calcium Release Channel

Identifiers

PMID18722380
PMCPMC3282562

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.