Trial reportJournal of the American Geriatrics Society2008
The influence of age on changes in health-related quality of life over three years in a cohort undergoing hemodialysis.
Trial report in Journal of the American Geriatrics Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Antidepressants for treating depression in adults with end-stage kidney disease treated with dialysis.The Cochrane database of systematic reviews · 2016Pooled it
- Quality of life profiles and their associations with depressive symptoms and cognitive impairment of community-dwelling older adults in Hong Kong.Frontiers in public health · 2023Article
- Health-Related Quality of Life and Disability Among Older New Zealanders With Kidney Failure: A Prospective Study.Canadian journal of kidney health and disease · 2022Article
- Quality of life may be a more valuable prognostic factor than depression in older hemodialysis patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Discussions during shared decision-making in older adults with advanced renal disease: a scoping review.BMJ open · 2019Article
- Treating symptoms to improve the quality of life in patients on chronic hemodialysis.International urology and nephrology · 2019Article
- The Role of Deprescribing in Older Adults with Chronic Kidney Disease.Drugs & aging · 2018Review
- Quality of Life-Repeated Measurements Are Needed In Dialysis Patients.Open access Macedonian journal of medical sciences · 2018Article
- Dialysis versus Medical Management at Different Ages and Levels of Kidney Function in Veterans with Advanced CKD.Journal of the American Society of Nephrology : JASN · 2018Article
- Differences in quality of life between Jewish and Arab patients on hemodialysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017Article
- Substitution of SF-36 by SF-12 Among Hong Kong Chinese Older Adults: Secondary Analysis of Randomized Controlled Trials.International journal of behavioral medicine · 2016Article
- Change in quality of life and one-year mortality risk in maintenance dialysis patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Article
- Sleep quality among Iranian hemodialysis patients: a multicenter study.Nephro-urology monthly · 2015Article
- Demographic factors affecting quality of life of hemodialysis patients - Lahore, Pakistan.Pakistan journal of medical sciences · 2014Article
- Chronic kidney disease and the aging population.Journal of cross-cultural gerontology · 2014Article
- Should an elderly patient with stage V CKD and dementia be started on dialysis?Clinical journal of the American Society of Nephrology : CJASN · 2014Article
- Chronic kidney disease and the aging population.Indian journal of nephrology · 2014Article
- Chronic kidney disease: chronic kidney disease and the ageing population.Nature reviews. Nephrology · 2014Article
- Chronic kidney disease and the aging population.Journal of nephrology · 2014Review
- Chronic kidney disease and the aging population.International journal of organ transplantation medicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesTo assess the extent to which persons aged 70 and older undergoing hemodialysis (HD) had greater changes in health-related quality of life (HRQOL) over 3 years than younger patients undergoing HD.
designLongitudinal.
settingThe Hemodialysis Study (HEMO Study) was a randomized, clinical trial of the effects of HD dose and membrane flux on mortality and morbidity in patients undergoing chronic dialysis.
participantsSecondary analysis of the HEMO Study. MEASUREMENTS: Participants completed the Index of Well-Being (IWB) and the Kidney Disease Quality of Life-Long Form (KDQOL-LF), which also includes the Medical Outcomes Study 36-item Short Form Questionnaire (SF-36) annually. Changes in subjects those aged 70 and older were compared with changes in subjects aged 55 to 69 and 18 to 54.
resultsAt baseline, 1,813 (98%) of HEMO participants completed HRQOL surveys. Their mean age was 58, 56% were female, 64% were black, and mean duration of dialysis was 3.8 years. In subjects with HRQOL data at the first three annual assessments, there were no substantial mean declines in the SF-36 Physical or Mental Component Summary scales over 3 years. In models incorporating effects of attrition, the differences in average change over 3 years between patients undergoing HD aged 70 and older and the younger cohorts were small in magnitude. There were high rates of adverse HRQOL events in all age groups and significantly higher composite event rates of death or clinically significant decline in HRQOL over 3 years was found in subjects aged 70 and older.
conclusionAlthough HRQOL was impaired in the population undergoing HD, HRQOL scores at baseline reflect a better-preserved multidimensional quality of life in respondents in the HEMO Study aged 70 and older than in younger patients undergoing HD. There was no substantial relationship between age and average decline in HRQOL score over 3 years in participants in the HEMO Study.
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