ArticleClinics (Sao Paulo, Brazil)2008
Heart rate dynamics during a treadmill cardiopulmonary exercise test in optimized beta-blocked heart failure patients.
Article in Clinics (Sao Paulo, Brazil), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Exercise training improves vascular function in patients with Alzheimer's disease.European journal of applied physiology · 2020Trial
- Comparison between physical and cognitive treatment in patients with MCI and Alzheimer's disease.Aging · 2019Trial
- Association between resting heart rate, chronotropic index, and long-term outcomes in patients with heart failure receiving β-blocker therapy: data from the HF-ACTION trial.European heart journal · 2013Trial
- Acute aerobic exercise reduces 24-h ambulatory blood pressure levels in long-term-treated hypertensive patients.Clinics (Sao Paulo, Brazil) · 2008Trial
- Norepinephrine remains increased in the six-minute walking test after heart transplantation.Clinics (Sao Paulo, Brazil) · 2010Article
- Electric countershock and cold stress effects on liver and adrenal gland.Clinics (Sao Paulo, Brazil) · 2010Article
- Hydrotherapy in heart failure: a case report.Clinics (Sao Paulo, Brazil) · 2009Article
- The relationship between heart rate reserve and oxygen uptake reserve in heart failure patients on optimized and non-optimized beta-blocker therapy.Clinics (Sao Paulo, Brazil) · 2008Article
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4 authors.
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Abstract
backgroundCalculating the maximum heart rate for age is one method to characterize the maximum effort of an individual. Although this method is commonly used, little is known about heart rate dynamics in optimized beta-blocked heart failure patients.
aimThe aim of this study was to evaluate heart rate dynamics (basal, peak and % heart rate increase) in optimized beta-blocked heart failure patients compared to sedentary, normal individuals (controls) during a treadmill cardiopulmonary exercise test.
methodsTwenty-five heart failure patients (49+/-11 years, 76% male), with an average LVEF of 30+/-7%, and fourteen controls were included in the study. Patients with atrial fibrillation, a pacemaker or noncardiovascular functional limitations or whose drug therapy was not optimized were excluded. Optimization was considered to be 50 mg/day or more of carvedilol, with a basal heart rate between 50 to 60 bpm that was maintained for 3 months.
resultsBasal heart rate was lower in heart failure patients (57+/-3 bpm) compared to controls (89+/-14 bpm; p<0.0001). Similarly, the peak heart rate (% maximum predicted for age) was lower in HF patients (65.4+/-11.1%) compared to controls (98.6+/-2.2; p<0.0001). Maximum respiratory exchange ratio did not differ between the groups (1.2+/-0.5 for controls and 1.15+/-1 for heart failure patients; p=0.42). All controls reached the maximum heart rate for their age, while no patients in the heart failure group reached the maximum. Moreover, the % increase of heart rate from rest to peak exercise between heart failure (48+/-9%) and control (53+/-8%) was not different (p=0.157).
conclusionNo patient in the heart failure group reached the maximum heart rate for their age during a treadmill cardiopulmonary exercise test, despite the fact that the percentage increase of heart rate was similar to sedentary normal subjects. A heart rate increase in optimized beta-blocked heart failure patients during cardiopulmonary exercise test over 65% of the maximum age-adjusted value should be considered an effort near the maximum. This information may be useful in rehabilitation programs and ischemic tests, although further studies are required.
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