ReviewCell cycle (Georgetown, Tex.)2008
Musashi1: a stem cell marker no longer in search of a function.
Review in Cell cycle (Georgetown, Tex.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 48 citations in OpenAlex.
- Dissecting RNA selectivity mediated by tandem RNA-binding domains.The Journal of biological chemistry · 2025Article
- Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer.Molecular and cellular biochemistry · 2025Review
- A novel method for culturing enteric neurons generates neurospheres containing functional myenteric neuronal subtypes.Journal of neuroscience methods · 2024Article
- Review
- Glioma Stem Cells in Pediatric High-Grade Gliomas: From Current Knowledge to Future Perspectives.Cancers · 2022Review
- Expression of Musashi-1 Increases in Bone Healing.International journal of molecular sciences · 2021Article
- Musashi-1 is the candidate of the regulator of hair cell progenitors during inner ear regeneration.BMC neuroscience · 2017Article
- Musashi2 promotes the development and progression of pancreatic cancer by down-regulating Numb protein.Oncotarget · 2017Article
- Musashi2 as a novel predictive biomarker for liver metastasis and poor prognosis in colorectal cancer.Cancer medicine · 2016Article
- Role of Msi1 and PYGO2 in esophageal squamous cell carcinoma depth of invasion.Journal of cell communication and signaling · 2016Article
- A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness.Stem cells (Dayton, Ohio) · 2015Article
- Putative stem cell markers in cervical squamous cell carcinoma are correlated with poor clinical outcome.BMC cancer · 2015Article
- Prognostic significance of neural stem cell markers, Nestin and Musashi-1, in oral squamous cell carcinoma: expression pattern of Nestin in the precancerous stages of oral squamous epithelium.Clinical oral investigations · 2015Article
- Heterogeneous generation of new cells in the adult echinoderm nervous system.Frontiers in neuroanatomy · 2015Article
- Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21, p27 and p53 in cervical carcinomas.Oncotarget · 2014Article
- Clinicopathological sex- related relevance of musashi1 mRNA expression in esophageal squamous cell carcinoma patients.Pathology oncology research : POR · 2014Article
- The RNA-binding protein Musashi-1 regulates proteasome subunit expression in breast cancer- and glioma-initiating cells.Stem cells (Dayton, Ohio) · 2014Article
- Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition.Journal of cellular and molecular medicine · 2014Article
- Blast crisis Ph+ chronic myeloid leukemia with NUP98/HOXA13 up-regulating MSI2.Molecular cytogenetics · 2014Article
- Mammary stem cell research in veterinary science: an update.Stem cells and development · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
One of the earliest genes identified with stem and early progenitor cells is the RNA-binding protein, Musashi1 (Msi1). Through gene profiling of mammary epithelial cells transduced with Msi1, a unique autocrine signaling pathway was identified that activates both the Wnt and Notch pathways. This process was associated with increased secretion of the growth factor, PLF1 and inhibition of the secreted Wnt pathway inhibitor, DKK3. Identification of PLF1 as an effector of these pathways in the absence of the DKK3 tumor suppressor provides a new avenue for investigating differences between normal and malignant tissues, and potentially targeting tumor stem cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.