ArticleAJNR. American journal of neuroradiology2008
Renal safety of CT angiography and perfusion imaging in the emergency evaluation of acute stroke.
Article in AJNR. American journal of neuroradiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Clinical and experimental nephrology · 2020Guideline
- Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version. JSN, JRS, and JCS Joint Working Group.Japanese journal of radiology · 2013Guideline
- Guidelines on the use of iodinated contrast media in patients with kidney disease 2012: digest version : JSN, JRS, and JCS Joint Working Group.Clinical and experimental nephrology · 2013Guideline
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- Disparities in Access to Vascular Stroke Imaging and Carotid Revascularization: A Population Study.Journal of the American Heart Association · 2025Article
- Cost-effectiveness of CT perfusion for the detection of large vessel occlusion acute ischemic stroke followed by endovascular treatment: a model-based health economic evaluation study.European radiology · 2024Article
- Post-Traumatic Cerebral Infarction: A Narrative Review of Pathophysiology, Diagnosis, and Treatment.Neurology international · 2024Review
- Incidence and risk factors of contrast-induced nephropathy in acute stroke patients undergoing computed tomography angiography: A single-center study.Neurosciences (Riyadh, Saudi Arabia) · 2023Article
- Changes in blood and renal function in patients after cerebral digital subtraction angiography.Research in diagnostic and interventional imaging · 2023Article
- Minimal Imaging Requirements.Journal of neuroendovascular therapy · 2023Review
- The Incidence and Associated Risk Factors of Contrast-Induced Nephropathy after Contrast-Enhanced Computed Tomography in the Emergency Setting: A Systematic Review.Life (Basel, Switzerland) · 2022Review
- Post-Contrast Acute Kidney Injury after Acute Stroke-Insights from a German Tertiary Care Center.Journal of clinical medicine · 2021Article
- Renal Safety of Repeated Intravascular Administrations of Iodinated or Gadolinium-Based Contrast Media within a Short Interval.Korean journal of radiology · 2021Article
- Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population.Neurointervention · 2021Review
- Save the Brain First: CTA and Mechanical Thrombectomy in Patients at Risk for Contrast-Induced Nephropathy.AJNR. American journal of neuroradiology · 2020Article
- Guideline on the use of iodinated contrast media in patients with kidney disease 2018.Japanese journal of radiology · 2020Article
- High White Blood Cell Count Is a Risk Factor for Contrast-Induced Nephropathy following Mechanical Thrombectomy for Acute Ischemic Stroke.Cerebrovascular diseases extra · 2020Article
- Incidence and Risk Factors of Postcontrast Acute Kidney Injury in Patients with Acute Ischemic Stroke.Stroke research and treatment · 2020Article
- Imaging of acute ischemic stroke.Emergency radiology · 2018Review
- Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeMultimodal CT imaging with contrast-enhanced CT angiography (CTA) and CT perfusion (CTP) is increasingly being used to guide emergency management of acute stroke. However, little has been reported about the safety of intravenous contrast administration associated with these studies in the acute stroke population, including cases in which baseline creatinine values are unknown. We investigated the incidence of contrast-induced nephropathy (CIN), defined as a 25% or more increase in baseline creatinine levels within 72 hours of contrast administration and chronic kidney disease in patients receiving CTA+/-CTP at our regional stroke center. MATERIALS AND
methodsWe analyzed 198 patients who underwent contrast CT studies for evaluation of acute ischemic or hemorrhagic stroke at our center (2003-2007). Through retrospective chart abstraction, we analyzed serial creatinine levels (baseline to day 3) and later values (>/=day 4) where available. The incidences of CIN and/or chronic kidney disease were documented. After power analysis, CIN and non-CIN groups were compared by using the unpaired t test, Wilcoxon rank sum test, or Fisher exact test.
resultsNone of the 198 patients developed chronic kidney disease or required dialysis. Of 175 patients with serial creatinine measurements between baseline and day 3, 5 (2.9%) developed CIN. The incidence of CIN was 2% in patients who were scanned before a baseline creatinine level was available.
conclusionThe incidence of renal sequelae is relatively low in acute stroke patients undergoing emergent multimodal CT scanning. Prompt CTA/CTP imaging of acute stroke, if indicated, need not be delayed in those with no history of renal impairment.
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