Evidence map›Paper›PMID 18718491›Full record

ArticleBehavioural brain research2009

Conditioned lick behavior and evoked responses using whisker twitches in head restrained rats.

Irina A Topchiy, Rachael M Wood, Breeanne Peterson, Jinna A Navas, Manuel J Rojas, David M Rector

Open access · greenAbstract read
In one paragraph

Article in Behavioural brain research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Push-in Head Restraining Apparatus for Intracranial Self Stimulation Tasks in Rats.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2014
    Article
  7. Sleep: a synchrony of cell activity-driven small network states.The European journal of neuroscience · 2013
    Review
  8. Article
  9. Article
  10. Article
  11. Physiological markers of local sleep.The European journal of neuroscience · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Irina A TopchiyCenter for Narcolepsy, Sleep and Health Research, Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, 840 South Wood Street (M/C 719), University of Illinois, Chicago, IL 60607, USA.
Rachael M Wood
Breeanne Peterson
Jinna A Navas
Manuel J Rojas
David M Rector
Washington State University · USSleepMed · USUniversidad Nacional de Colombia · CO

Funding

ADVANCED OPTICAL IMAGE PROBE FOR NEUROPHYSIOLOGYR01MH060263 · NIMH · WASHINGTON STATE UNIVERSITY · PI RECTOR, DAVID M · 2001 to 2009
$2.8M
NIMH NIH HHS MH60263NIMH NIH HHS R01 MH060263
6 · The paper itself

Abstract

To examine whisker barrel evoked response potentials in chronically implanted rats during behavioral learning with very fast response times, rats must be calm while immobilized with their head restrained. We quantified their behaviors during training with an ethogram and measured each individual animals' progress over the training period. Once calm under restraint, rats were conditioned to differentiate between a reward and control whisker twitch, then provide a lick response when presented with the correct stimulus, rewarded by a drop of water. Rats produced the correct licking response (after reward whisker twitch), and learned not to lick after a control whisker was twitched. By implementing a high-density 64-channel electrocorticogram (ECoG) electrode array, we mapped the barrel field of the somatosensory cortex with high spatial and temporal resolution during conditioned lick behaviors. In agreement with previous reports, we observe a larger evoked response after training, probably related to mechanisms of cortical plasticity.

Indexed as

Brain MappingAdaptation, PhysiologicalAdaptation, PsychologicalAnimalsConditioning, OperantDiscrimination LearningDrinking BehaviorEvoked Potentials, SomatosensoryFemaleHabituation, PsychophysiologicNeural PathwaysPhysical StimulationRatsRats, Sprague-DawleyReaction TimeRestraint, Physical

Identifiers

PMID18718491
PMCPMC2607480
OpenAlexW2024544573

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.