Blame vaccine interference, not neonatal immunization, for suboptimal responses after neonatal diphtheria, tetanus, and acellular pertussis immunization.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. Immunogenicity and Safety of Monovalent Acellular Pertussis Vaccine at Birth: A Randomized Clinical Trial.JAMA pediatrics · 2018
   Trial
2. Efficacy, Immunogenicity, and Safety of Pertussis Vaccine During Pregnancy: A Meta-Analysis.Vaccines · 2025
   Review
3. Influence of the H1N1 influenza pandemic on the humoral immune response to seasonal flu vaccines.PloS one · 2021
   Article
4. Vaccination strategies to enhance immunity in neonates.Science (New York, N.Y.) · 2020
   Review
5. Neonatal vaccine effectiveness and the role of adjuvants.Expert review of clinical immunology · 2019
   Review
6. Vaccine responses in newborns.Seminars in immunopathology · 2017
   Review
7. Maternal pertussis immunisation: clinical gains and epidemiological legacy.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2017
   Article
8. Protecting newborns from pertussis - the challenge of complete cocooning.BMC infectious diseases · 2014
   Article
9. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: neonatal immune function and vaccine responses in children born in low-income versus high-income countries.Clinical and experimental immunology · 2010
   Article
10. B-cell responses to vaccination at the extremes of age.Nature reviews. Immunology · 2009
    Review

Corrections and comments

• Comment on
  Poor immune responses to a birth dose of diphtheria, tetanus, and acellular pertussis vaccine.2008

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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