ArticleAnimal genetics2008
Linkage disequilibrium and signatures of selection on chromosomes 19 and 29 in beef and dairy cattle.
Article in Animal genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Meta-Assembly of Selection Signatures in Cattle.PloS one · 2016Pooled it
- Global and Local Ancestry and its Importance: A Review.Current genomics · 2024Review
- Identification of Loci and Pathways Associated with Heifer Conception Rate in U.S. Holsteins.Genes · 2020Article
- Identification of loci associated with conception rate in primiparous Holstein cows.BMC genomics · 2019Article
- Population Genomic Structure and Genome-Wide Linkage Disequilibrium in Farmed Atlantic Salmon (Frontiers in genetics · 2018Article
- An interpretive review of selective sweep studies in Bos taurus cattle populations: identification of unique and shared selection signals across breeds.Frontiers in genetics · 2015Review
- A genome-wide scan for selection signatures in Yorkshire and Landrace pigs based on sequencing data.Animal genetics · 2014Article
- Identification of selection signatures in livestock species.Genetics and molecular biology · 2014Review
- A genome-wide scan of selective sweeps in two broiler chicken lines divergently selected for abdominal fat content.BMC genomics · 2012Article
- Article
- Genomic scan of selective sweeps in thin and fat tail sheep breeds for identifying of candidate regions associated with fat deposition.BMC genetics · 2012Article
- Combining evidence of selection with association analysis increases power to detect regions influencing complex traits in dairy cattle.BMC genomics · 2012Article
- Linkage disequilibrium in Angus, Charolais, and Crossbred beef cattle.Frontiers in genetics · 2012Article
- Accuracies of genomic breeding values in American Angus beef cattle using K-means clustering for cross-validation.Genetics, selection, evolution : GSE · 2011Article
- Identification of selection signatures in cattle breeds selected for dairy production.Genetics · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to quantify the extent of linkage disequilibrium (LD) on bovine chromosomes 19 and 29 and to study the pattern of selection signatures in beef and dairy breeds (Angus and Holstein) of Bos taurus. The extent of LD was estimated for 370 and 186 single nucleotide polymorphism markers on BTA19 and 29 respectively using the square of the correlation coefficient (r(2)) among alleles at pairs of loci. A comparison of the extent of LD found that the decline of LD followed a similar pattern in both breeds. We observed long-range LD and found that LD dissipates to background levels at a locus separation of about 20 Mb on both chromosomes. Along each chromosome, patterns of LD were variable in both breeds. We find that a minimum of 30 000 informative and evenly spaced markers would be required for whole-genome association studies in cattle. In addition, we have identified chromosomal regions that show some evidence of selection for economically important traits in Angus and Holstein cattle. The results of this study are of importance for the design and application of association studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.