Evidence map›Paper›PMID 18716848›Full record

ArticleJournal of general internal medicine2008

National evaluation of policies on individual financial conflicts of interest in Canadian academic health science centers.

Joel Lexchin, Melanie Sekeres, Jennifer Gold, Lorraine E Ferris, Sunila R Kalkar, Wei Wu, Marleen Van Laethem, An-Wen Chan, David Moher, M James Maskalyk and 2 more

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Correlation between financial relationships with commercial interests and research prominence at an oncology meeting.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2013
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joel LexchinSchool of Health Policy and Management, York University, Toronto, ON, Canada. jlexchin@yorku.ca
Melanie Sekeres
Jennifer Gold
Lorraine E Ferris
Sunila R Kalkar
Wei Wu
Marleen Van Laethem
An-Wen Chan
David Moher
M James Maskalyk
Nathan Taback
Paula A Rochon

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConflicts of interest (COI) in research are an important emerging topic of investigation and are frequently cited as a serious threat to the integrity of human participant research.

objectiveTo study financial conflicts of interest (FCOI) policies for individual investigators working in Canadian academic health centers.

designSurvey instrument containing 61 items related to FCOI.

settingAll Canadian academic health science centers (universities with faculties of medicine, faculties of medicine and teaching hospitals) were requested to provide their three primary FCOI policies. MEASUREMENTS: Number of all centers and teaching hospitals with policies addressing each of the 61 items related to FCOI. MAIN

resultsOnly one item was addressed by all 74 centers. Thirteen items were present in fewer than 25% of centers. Fewer than one-quarter of hospitals required researchers to disclose FCOI to research participants. The role of research ethics boards (REBs) in hospitals was marginal. LIMITATIONS: Asking centers to identify only three policies may not have inclusively identified all FCOI policies in use. Additionally, policies at other levels might apply. For instance, all institutions receiving federal grant money must comply with the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans.

conclusionsCanadian centers within the same level (for instance, teaching hospitals) differ significantly in the areas that their policies address and these policies differ widely in their coverage. Presently, no single policy in any Canadian center informs researchers about the broad range of individual FCOI issues. Canadian investigators need to understand the environment surrounding FCOI, be able to access and follow the relevant policies and be confident that they can avoid entering into a FCOI.

Indexed as

Academic Medical CentersCanadaConflict of InterestData CollectionDisclosureHumansResearch

Identifiers

PMID18716848
PMCPMC2585679

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.