Evidence map›Paper›PMID 18713140›Full record

ReviewClinical and experimental immunology2008

Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease.

P C Dubois, D A van Heel

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 56 citations in OpenAlex.

  1. Trial
  2. International journal of molecular sciences · 2025
    Article
  3. Article
  4. Gluten-degrading bacteria: availability and applications.Applied microbiology and biotechnology · 2021
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Serological testing for celiac disease in adults.United European gastroenterology journal · 2013
    Article
  10. Article
  11. Article
  12. Immune development and intestinal microbiota in celiac disease.Clinical & developmental immunology · 2012
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

P C DuboisInstitute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, London, UK. p.c.dubois@qmul.ac.uk
D A van Heel
Queen Mary University of London · GB

Funding

Medical Research Council
6 · The paper itself

Abstract

Recent advances in immunological and genetic research in coeliac disease provide new and complementary insights into the immune response driving this chronic intestinal inflammatory disorder. Both approaches confirm the central importance of T cell-mediated immune responses to disease pathogenesis and have further begun to highlight other relevant components of the mucosal immune system, including innate immunity and the control of lymphocyte trafficking to the mucosa. In the last year, the first genome wide association study in celiac disease led to the identification of multiple new risk variants. These risk regions implicate genes involved in the immune system. Overlap with autoimmune diseases is striking with several of these regions being shown to confer susceptibility to other chronic immune-mediated diseases, particularly type 1 diabetes.

Indexed as

ImmunogeneticsAntigensAutoimmunityCeliac DiseaseForecastingGastrointestinal TractGenetic Predisposition to DiseaseGlutensHumansImmunity, InnateAntigensGlutens

Identifiers

PMID18713140
PMCPMC2492906
OpenAlexW2143998769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.