Evidence map›Paper›PMID 18712399›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2009

Atypical basal ganglia germinoma presenting as cerebral hemiatrophy: diagnosis and follow-up with 11C-methionine positron emission tomography.

Jeehun Lee, Bo Lyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Su Jin Lee, Joon Young Choi, Kyung-Han Lee, Jung Il Lee, Hyung-Jin Shin and 4 more

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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Germinoma of basal ganglia.Radiology case reports · 2024
    Article
  3. Multiple ectopic germinomas presenting as focal dystonia of fingers: a case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Clinico-radiological approach to cerebral hemiatrophy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Latency of intracranial germ cell tumors and diagnosis delay.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013
    Article
  14. Review
  15. Article
  16. Use of 11C-methionine positron emission tomography in basal germinoma: assessment of treatment response and residual tumor.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2009
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Jeehun LeeDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Bo Lyun Lee
Keon Hee Yoo
Ki Woong Sung
Hong Hoe Koo
Su Jin Lee
Joon Young Choi
Kyung-Han Lee
Jung Il Lee
Hyung-Jin Shin
Ji Hye Kim
Yeon Lim Suh
Ke Hyang Lee
Munhyang Lee
Sungkyunkwan University · KRSamsung Medical Center · KRCatholic University of Daegu · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectsSome basal ganglia germinomas are difficult to diagnose in early stage of disease due to vague initial presentation without discernable mass lesion on brain imaging. We performed this study to determine the usefulness of 11C-methionine positron emission tomography (MET PET) for the diagnosis and monitoring of disease activity. MATERIALS AND

methodsMET PET was performed in three consecutive patients; they presented with cerebral hemiatrophy without definite mass lesions on brain image. The maximum standard tracer uptake values (max SUVs) were calculated and used for the quantitative evaluation of the abnormal MET uptake. A pathological diagnosis was made after stereotactic biopsy using MET PET/computed tomography. The max SUVs significantly decreased after treatment.

conclusionBasal ganglia germinoma should be considered in the differential diagnosis of patients with progressive hemiparesis and hemiatrophy on magnetic resonance imaging. The MET PET was useful for diagnosis, and it can be valuable in evaluation of treatment effects and monitoring for tumor recurrence.

Indexed as

AdolescentAtrophyBasal GangliaBrain NeoplasmsCarbon RadioisotopesCerebral CortexChildDiagnosis, DifferentialGerminomaHumansMagnetic Resonance ImagingMaleMethioninePositron-Emission TomographyCarbon RadioisotopesMethionine

Identifiers

PMID18712399
OpenAlexW2080493514

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.