Maximizing rates of empiric appropriate antibiotic therapy with minimized use of broad-spectrum agents: are surveillance cultures the key?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Value of lower respiratory tract surveillance cultures to predict bacterial pathogens in ventilator-associated pneumonia: systematic review and diagnostic test accuracy meta-analysis.Intensive care medicine · 2013
   Pooled it
2. The threat of multidrug-resistant/extensively drug-resistant Gram-negative respiratory infections: another pandemic.European respiratory review : an official journal of the European Respiratory Society · 2022
   Article
3. Derivation and validation of a simple score to predict the presence of bacteria requiring carbapenem treatment in ICU-acquired bloodstream infection and pneumonia: CarbaSCORE.Antimicrobial resistance and infection control · 2019
   Article
4. Microbiological profile of organisms causing bloodstream infection in critically ill patients.Journal of clinical medicine research · 2012
   Article
5. Assessment of microbial diversity in biofilms recovered from endotracheal tubes using culture dependent and independent approaches.PloS one · 2012
   Article
6. The rising problem of antimicrobial resistance in the intensive care unit.Annals of intensive care · 2011
   Article

Corrections and comments

• Comment on
  Screening for resistant gram-negative microorganisms to guide empiric therapy of subsequent infection.2008
• Comment on
  Previous endotracheal aspirate allows guiding the initial treatment of ventilator-associated pneumonia.2009

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as