ArticleAntimicrobial agents and chemotherapy2008
Vibrio cholerae O139 multiple-drug resistance mediated by Yersinia pestis pIP1202-like conjugative plasmids.
Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 73 citations in OpenAlex.
- Characterisation and mobilisation of IncA/C plasmid-mediated antibiotic resistance in Edwardsiella ictaluri.Journal of global antimicrobial resistance · 2023Article
- Resistome Study in Aquatic Environments.Journal of microbiology and biotechnology · 2023Review
- Resistance ofFrontiers in pharmacology · 2023Review
- Differences in substrate specificity of V. cholerae FabH enzymes suggest new approaches for the development of novel antibiotics and biofuels.The FEBS journal · 2018Article
- Article
- Reduced Susceptibility to Extended-Spectrum β-Lactams inFrontiers in public health · 2016Article
- In Vivo Transmission of an IncA/C Plasmid in Escherichia coli Depends on Tetracycline Concentration, and Acquisition of the Plasmid Results in a Variable Cost of Fitness.Applied and environmental microbiology · 2015Article
- Insight into the mobilome of Aeromonas strains.Frontiers in microbiology · 2015Review
- Development of pVCR94ΔX from Vibrio cholerae, a prototype for studying multidrug resistant IncA/C conjugative plasmids.Frontiers in microbiology · 2014Article
- Multiple Pathways of Genome Plasticity Leading to Development of Antibiotic Resistance.Antibiotics (Basel, Switzerland) · 2013Review
- Transcriptome mapping of pAR060302, a blaCMY-2-positive broad-host-range IncA/C plasmid.Applied and environmental microbiology · 2012Article
- Group IIC intron with an unusual target of integration in Enterobacter cloacae.Journal of bacteriology · 2012Article
- Multiple antibiotic resistance of Vibrio cholerae serogroup O139 in China from 1993 to 2009.PloS one · 2012Article
- Article
- Selection pressure required for long-term persistence of blaCMY-2-positive IncA/C plasmids.Applied and environmental microbiology · 2011Article
- Antimicrobials & cholera: are we stranded?The Indian journal of medical research · 2011Review
- Salmonella Typhimurium ST213 is associated with two types of IncA/C plasmids carrying multiple resistance determinants.BMC microbiology · 2011Article
- Article
- ISCR elements are key players in IncA/C plasmid evolution.Antimicrobial agents and chemotherapy · 2010Article
- blaCMY-2-positive IncA/C plasmids from Escherichia coli and Salmonella enterica are a distinct component of a larger lineage of plasmids.Antimicrobial agents and chemotherapy · 2010Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A conjugative plasmid, pMRV150, which mediated multiple-drug resistance (MDR) to at least six antibiotics, including ampicillin, streptomycin, gentamicin, tetracycline, chloramphenicol, and trimethoprim-sulfamethoxazole, was identified in a Vibrio cholerae O139 isolate from Hangzhou, eastern China, in 2004. According to partial pMRV150 DNA sequences covering 15 backbone regions, the plasmid is most similar to pIP1202, an IncA/C plasmid in an MDR Yersinia pestis isolate from a Madagascar bubonic plague patient, at an identity of 99.99% (22,180/22,183 nucleotides). pMRV150-like plasmids were found in only 7.69% (1/13) of the O139 isolates tested during the early period of the O139 epidemic in Hangzhou (1994, 1996, and 1997); then the frequency increased gradually from 60.00% (3/5) during 1998 and 1999 to 92.16% (47/51) during 2000 to 2006. Most (42/51) of the O139 isolates bearing pMRV150-like plasmids were resistant to five to six antibiotics, whereas the plasmid-negative isolates were resistant only to one to three antibiotics. In 12 plasmid-bearing O139 isolates tested, the pMRV150-like plasmids ranged from approximately 140 kb to 170 kb and remained at approximately 1 or 2 copies per cell. High (4.50 x 10(-2) and 3.08 x 10(-2)) and low (0.88 x 10(-8) to 3.29 x 10(-5)) plasmid transfer frequencies, as well as no plasmid transfer (under the detection limit), from these O139 isolates to the Escherichia coli recipient were observed. The emergence of pMRV150-like or pIP1202-like plasmids in many bacterial pathogens and nonpathogens occupying diverse niches with global geographical distribution indicates an increasing risk to public health worldwide. Careful tracking of these plasmids in the microbial ecosystem is warranted.
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