ReviewRespiratory physiology & neurobiology2008
Trophic factor expression in phrenic motor neurons.
Review in Respiratory physiology & neurobiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 34 citations in OpenAlex.
- Motor Neuron Size-Dependent Differences in mRNA Expression of Tropomyosin-Related Kinase Receptor B in Adult Rats.Journal of neurochemistry · 2026Article
- Inhibition of TrkB kinase activity impairs autophagy in cervical motor neurons of young but not old mice.Experimental physiology · 2025Article
- Electrophysiological effects of BDNF and TrkB signaling at type-identified diaphragm neuromuscular junctions.Journal of neurophysiology · 2023Article
- TrkB signaling contributes to transdiaphragmatic pressure generation in aged mice.Journal of neurophysiology · 2021Article
- Inhibition of TrkB kinase activity impairs transdiaphragmatic pressure generation.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- A Critical Evaluation of Current Concepts in Cerebral Palsy.Physiology (Bethesda, Md.) · 2019Review
- Evolution and Functional Differentiation of the Diaphragm Muscle of Mammals.Comprehensive physiology · 2019Review
- Phrenic motoneuron structural plasticity across models of diaphragm muscle paralysis.The Journal of comparative neurology · 2018Article
- Differences in lumbar motor neuron pruning in an animal model of early onset spasticity.Journal of neurophysiology · 2018Article
- Functional recovery after cervical spinal cord injury: Role of neurotrophin and glutamatergic signaling in phrenic motoneurons.Respiratory physiology & neurobiology · 2016Review
- Role of TrkB during the postnatal development of the rat carotid body.Respiratory physiology & neurobiology · 2015Article
- Ageing and neurotrophic signalling effects on diaphragm neuromuscular function.The Journal of physiology · 2015Article
- TrkB kinase activity is critical for recovery of respiratory function after cervical spinal cord hemisection.Experimental neurology · 2014Article
- TrkB kinase activity maintains synaptic function and structural integrity at adult neuromuscular junctions.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Article
- CrossTalk opposing view: The diaphragm muscle does not atrophy as a result of inactivity.The Journal of physiology · 2013Article
- Anatomic connections of the diaphragm: influence of respiration on the body system.Journal of multidisciplinary healthcare · 2013Article
- Respiratory muscle plasticity.Comprehensive Physiology · 2012Review
- Neuregulin-1 at synapses on phrenic motoneurons.The Journal of comparative neurology · 2010Article
- Role of neurotrophins in recovery of phrenic motor function following spinal cord injury.Respiratory physiology & neurobiology · 2009Review
- Neuromuscular adaptations to respiratory muscle inactivity.Respiratory physiology & neurobiology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The function of a motor neuron and the muscle fibers it innervates (i.e., a motor unit) determines neuromotor output. Unlike other skeletal muscles, respiratory muscles (e.g., the diaphragm, DIAm) must function from birth onwards in sustaining ventilation. DIAm motor units are capable of both ventilatory and non-ventilatory behaviors, including expulsive behaviors important for airway clearance. There is significant diversity in motor unit properties across different types of motor units in the DIAm. The mechanisms underlying the development and maintenance of motor unit diversity in respiratory muscles (including the DIAm) are not well understood. Recent studies suggest that trophic factor influences contribute to this diversity. Remarkably little is known about the expression of trophic factors and their receptors in phrenic motor neurons. This review will focus on the contribution of trophic factors to the establishment and maintenance of motor unit diversity in the DIAm, during development and in response to injury or disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.