ArticleMolecular plant pathology2008
Indole-3-acetic acid (IAA) biosynthesis in the smut fungus Ustilago maydis and its relevance for increased IAA levels in infected tissue and host tumour formation.
Article in Molecular plant pathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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78 citing papers in PubMed, 176 citations in OpenAlex.
- Indole-3-Acetic Acid Biosynthesis by Endophytic Fungi and Its Association with Plant-Fungus Interactions.Journal of fungi (Basel, Switzerland) · 2026Review
- Hormone variation in Robinia pseudoacacia L. (Fabaceae) leaves during gall formation by Oblongoides robiniae (Haldeman) (Diptera: Cecidomyiidae).Scientific reports · 2026Article
- Pathogenic fungus Ustilago maydis exploits the lateral root regulators to induce pluripotency in maize shoots.The New phytologist · 2026Article
- Auxin accumulation in cereals after infection by Fusarium graminearum: putative biosynthetic pathways and preferences.Stress biology · 2026Review
- Auxin dysregulation: a key early event in sugarcane susceptibility to Sporisorium scitamineum.BMC plant biology · 2026Article
- Nitrogen deficiency restricts gall development by altering metabolic and hormonal networks inFrontiers in plant science · 2026Article
- A putative auxin efflux carrier FgAec1 contributes to the pathogenicity of Fusarium graminearum.BMC biology · 2025Article
- Interactions with native microbial keystone taxa enhance the biocontrol efficiency of Streptomyces.Microbiome · 2025Article
- Engineering probiotic Escherichia coli for inflammation-responsive indoleacetic acid production using RiboJ-enhanced genetic circuits.Journal of biological engineering · 2025Article
- Discovery of Two Novel Phthalide Phytotoxins from the Wheat Tan Spot Fungal PathogenJournal of agricultural and food chemistry · 2024Article
- Physiological Mechanisms Underlying Tassel Symptom Formation in Maize Infected withPlants (Basel, Switzerland) · 2024Article
- Adaptation ofFrontiers in plant science · 2024Article
- Manipulation of Auxin Signaling by Smut Fungi during Plant Colonization.Journal of fungi (Basel, Switzerland) · 2023Review
- Physiological Effects of Microbial Biocontrol Agents in the Maize Phyllosphere.Plants (Basel, Switzerland) · 2023Review
- Herbicide 2,4-dichlorophenoxyacetic acid interferes with MAP kinase signaling in Fusarium graminearum and is inhibitory to fungal growth and pathogenesis.Stress biology · 2023Article
- Differences in the Production of Extracellular Polymeric Substances (EPS) and Other Metabolites ofMetabolites · 2023Article
- Genomic Assessment of the Contribution of theInternational journal of molecular sciences · 2023Article
- Progress in pathogenesis research of Ustilago maydis, and the metabolites involved along with their biosynthesis.Molecular plant pathology · 2023Review
- Aminotransferase SsAro8 Regulates Tryptophan Metabolism Essential for Filamentous Growth of Sugarcane Smut FungusMicrobiology spectrum · 2022Article
- Differential Regulation and Production of Secondary Metabolites among Isolates of the Fungal Wheat Pathogen Zymoseptoria tritici.Applied and environmental microbiology · 2022Article
18 more citing papers are in PubMed but not listed here.
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6 authors at 2 institutions in 1 country.
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Abstract
Infection of maize (Zea mays) plants with the smut fungus Ustilago maydis is characterized by excessive host tumour formation. U. maydis is able to produce indole-3-acetic acid (IAA) efficiently from tryptophan. To assess a possible connection to the induction of host tumours, we investigated the pathways leading to fungal IAA biosynthesis. Besides the previously identified iad1 gene, we identified a second indole-3-acetaldehyde dehydrogenase gene, iad2. Deltaiad1Deltaiad2 mutants were blocked in the conversion of both indole-3-acetaldehyde and tryptamine to IAA, although the reduction in IAA formation from tryptophan was not significantly different from Deltaiad1 mutants. To assess an influence of indole-3-pyruvic acid on IAA formation, we deleted the aromatic amino acid aminotransferase genes tam1 and tam2 in Deltaiad1Deltaiad2 mutants. This revealed a further reduction in IAA levels by five- and tenfold in mutant strains harbouring theDeltatam1 andDeltatam1Deltatam2 deletions, respectively. This illustrates that indole-3-pyruvic acid serves as an efficient precursor for IAA formation in U. maydis. Interestingly, the rise in host IAA levels upon U. maydis infection was significantly reduced in tissue infected with Deltaiad1Deltaiad2Deltatam1 orDeltaiad1Deltaiad2Deltatam1Deltatam2 mutants, whereas induction of tumours was not compromised. Together, these results indicate that fungal IAA production critically contributes to IAA levels in infected tissue, but this is apparently not important for triggering host tumour formation.
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