ReviewJournal of mammary gland biology and neoplasia2008
The relevance of mouse models to understanding the development and progression of human breast cancer.
Review in Journal of mammary gland biology and neoplasia, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Modeling Human Ductal Carcinoma In Situ in the Mouse.Journal of mammary gland biology and neoplasia · 2018Review
- Effect of a tissue selective estrogen complex on breast cancer: Role of unique properties of conjugated equine estrogen.International journal of cancer · 2018Article
- Canine mammary tumors as a model for human disease.Oncology letters · 2018Review
- Screening and analysis of breast cancer genes regulated by the human mammary microenvironment in a humanized mouse model.Oncology letters · 2016Article
- High mammographic breast density predicts locoregional recurrence after modified radical mastectomy for invasive breast cancer: a case-control study.Breast cancer research : BCR · 2016Article
- Establishment and characterization of a new feline mammary cancer cell line, FkMTp.Cytotechnology · 2016Article
- Human mammary microenvironment better regulates the biology of human breast cancer in humanized mouse model.Medical oncology (Northwood, London, England) · 2015Article
- BST-2/tetherin is overexpressed in mammary gland and tumor tissues in MMTV-induced mammary cancer.Virology · 2013Article
- Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer.Cancer research · 2012Article
- Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors.Hormones & cancer · 2012Article
- Pregnancy-induced changes in breast cancer risk.Journal of mammary gland biology and neoplasia · 2011Review
- Progesterone receptor action: defining a role in breast cancer.Expert review of endocrinology & metabolism · 2011Article
- Cx43 suppresses mammary tumor metastasis to the lung in a Cx43 mutant mouse model of human disease.Oncogene · 2011Article
- β1-integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer.Breast cancer research : BCR · 2011Review
- Of mice and women: A short history of mouse mammary cancer research with an emphasis on the paradigms inspired by the transplantation method.Cold Spring Harbor perspectives in biology · 2010Review
- Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response.Endocrine-related cancer · 2010Review
- Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis.Carcinogenesis · 2010Article
- Article
- Pituitary tumor transforming gene binding factor: a new gene in breast cancer.Cancer research · 2010Article
- Spontaneous feline mammary intraepithelial lesions as a model for human estrogen receptor- and progesterone receptor-negative breast lesions.BMC cancer · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mouse modeling of human breast cancer has developed tremendously over the past ten years. Human breast cancer is characterized by enormous biological diversity and, collectively, the new models have come much closer to encompassing this diversity. They have provided a deeper understanding of the fundamental events that mediate the initiation, development, and progression of breast cancer, and they offer new opportunities to develop and test strategies to treat and, perhaps, even prevent the disease. This chapter reviews the historical development of mouse models of breast cancer and highlights some of their major strengths, weaknesses, and contributions.
Indexed as
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18704660What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.