Evidence map›Paper›PMID 18703545›Full record

ArticleArchives of disease in childhood2009

Environmental exposures and respiratory morbidity among very low birth weight infants at 1 year of life.

J S Halterman, K A Lynch, K M Conn, T E Hernandez, T T Perry, T P Stevens

Abstract read
In one paragraph

Article in Archives of disease in childhood, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Is there a link between wheezing in early childhood and adverse birth outcomes? A systematic review.International journal of environmental research and public health · 2009
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Influences of environmental exposures on preterm lung disease.Expert review of respiratory medicine · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Tobacco smoke in infants with bronchopulmonary dysplasia.European journal of pediatrics · 2015
    Article
  15. Respiratory consequences of prematurity: evolution of a diagnosis and development of a comprehensive approach.Journal of perinatology : official journal of the California Perinatal Association · 2015
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Exploring modifiable risk factors for wheezing in African American premature infants.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J S HaltermanDepartment of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA. jill_halterman@urmc.rochester.edu
K A Lynch
K M Conn
T E Hernandez
T T Perry
T P Stevens

Funding

Oxygen, Oxidant Stress and Wheezing in Premature InfantsK23HD050646 · NICHD · UNIVERSITY OF ROCHESTER · PI STEVENS, TIMOTHY P · 2006 to 2010
$625k
NICHD NIH HHS HD050646NICHD NIH HHS K23 HD050646
6 · The paper itself

Abstract

introductionPreterm infants have a substantially increased risk of developing respiratory illnesses. The goal of this study was to consider the impact of modifiable postnatal exposures on respiratory morbidity among a cohort of very low birth weight (VLBW) infants.

objectives(1) Assess the rates of respiratory morbidity and exposure to indoor respiratory triggers in a population of VLBW infants at 1 year; (2) determine the association between exposures and respiratory morbidity.

methodsWe enrolled 124 VLBW infants into a prospective cohort study. Parents were called at 1 year to assess respiratory outcomes and environmental exposures. We used bivariate and multivariate analyses to assess the relationship between environmental exposures and acute care for respiratory illnesses.

resultsAt 1 year, 9% of infants had physician-diagnosed asthma, 47% required >or=1 acute visit and 11% required hospitalisation for respiratory illness. The majority of infants (82%) were exposed to at least one indoor respiratory trigger. Infants living with a smoker (61% vs 40%) and infants exposed to pests (62% vs 39%) were more likely than unexposed infants to require acute care for respiratory problems. In a multivariate regression controlling for demographics, birth weight, bronchopulmonary dysplasia, and family history of asthma or allergies, both living with a smoker (OR 2.62; CI 1.09 to 6.29) and exposure to pests (OR 4.41; CI 1.22 to 15.94) were independently associated with the need for acute care for respiratory illnesses.

conclusionsIn this sample, respiratory morbidity and exposure to triggers were common. VLBW infants may benefit from interventions that decrease exposure to respiratory triggers.

Indexed as

Infant, Very Low Birth WeightAir Pollution, IndoorAsthmaEnvironmental ExposureFemaleHospitalizationHumansInfantInfant, NewbornMaleMultivariate AnalysisOxygen Inhalation TherapyProspective StudiesRespiratory SoundsRisk FactorsSmoking

Identifiers

PMID18703545
PMCPMC5279900

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.