ArticleDrug discovery today. Disease mechanisms2007
Ischemic Preconditioning And Myocardial Infarction: An Update and Perspective.
Article in Drug discovery today. Disease mechanisms, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- The Enhanced Effects of Swimming and Running Preconditioning in an Experimental Model of Myocardial Ischemia/Reperfusion Injury.Medicina (Kaunas, Lithuania) · 2023Article
- Endless Journey of Adenosine Signaling in Cardioprotective Mechanism of Conditioning Techniques: Clinical Evidence.Current cardiology reviews · 2023Review
- Effects of swimming training on myocardial protection in rats.Biomedical reports · 2022Article
- Clinical Applicability of Conditioning Techniques in Ischemia-Reperfusion Injury: A Review of the Literature.Current cardiology reviews · 2021Review
- Involvement of p53 in the Responses of Cardiac Muscle Cells to Heat Shock Exposure and Heat Acclimation.Journal of cardiovascular translational research · 2020Article
- Effluent from ischemic preconditioned hearts confers cardioprotection independent of the number of preconditioning cycles.PloS one · 2020Article
- Profiling of cell stress protein expression in cardiac tissue of cardiosurgical patients undergoing remote ischemic preconditioning: implications for thioredoxin in cardioprotection.Journal of translational medicine · 2015Article
- Activities of cardiac tissue matrix metalloproteinases 2 and 9 are reduced by remote ischemic preconditioning in cardiosurgical patients with cardiopulmonary bypass.Journal of translational medicine · 2014Article
- Article
- Hydrogen sulfide preconditioning or neutrophil depletion attenuates ischemia-reperfusion-induced mitochondrial dysfunction in rat small intestine.American journal of physiology. Gastrointestinal and liver physiology · 2012Article
- Targeting of adenosine receptors in ischemia-reperfusion injury.Expert opinion on therapeutic targets · 2011Review
- Mechanism of cardioprotective effect of erythropoietin-induced preconditioning in rat heart.Indian journal of pharmacology · 2010Article
- Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2.The Journal of biological chemistry · 2009Article
- Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning.American journal of physiology. Heart and circulatory physiology · 2009Article
- Cellular and molecular neurobiology of brain preconditioning.Molecular neurobiology · 2009Review
- Protection of the ischaemic heart: investigations into the phenomenon of ischaemic preconditioning.Cardiovascular journal of AfricaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Myocardial infarction is the leading cause of mortality in Western societies with annual expenditures of $431.8 billion spent on coronary artery disease in man. Therapeutics to combat infarction from myocardial injury, based on studies of ischemic preconditioning (IPC), are currently in progress. Hence, this review provides an update on IPC, including general and molecular mechanisms responsible for IPC and the effects of IPC in models of aging or disease. A summary of therapeutics shown to possess efficacy in preclinical and clinical trials and future directions of studies regarding cardiac IPC are also discussed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.