ArticlePlant physiology2008
Putrescine is involved in Arabidopsis freezing tolerance and cold acclimation by regulating abscisic acid levels in response to low temperature.
Article in Plant physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.
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121 citing papers in PubMed, 392 citations in OpenAlex.
- Abscisic acid interplay with phytohormones, plant growth regulators and signaling molecules in orchestrating an elaborate crosstalk for stress resilience in plants.Biologia futura · 2026Review
- Dual functions of thermospermine in plant growth and stress responses.Amino acids · 2026Review
- Melatonin enhances the cold tolerance of tomatoes by promoting ABA accumulation.Plant cell reports · 2026Article
- Mangrove derived coactive bacterial inoculant triggered biochemical traits rejuvenating plant cell function under salt stress.Plant cell reports · 2025Article
- When Warm Breaks Cold: Understanding Deacclimations and Reacclimations Cycles as a Key to Winter Crop Resilience.International journal of molecular sciences · 2025Review
- A multi-layered systems biology framework reveals dual-phased regulators and hormonal crosstalk underlying soybean cold tolerance.Plant cell reports · 2025Article
- Genome-Wide Identification, Phylogenetic Analysis, and Expression Pattern of Polyamine Biosynthesis Gene Family in Pepper.International journal of molecular sciences · 2025Article
- Chemical application improves stress resilience in plants.Plant molecular biology · 2025Review
- Serotonin Mitigates ColdStress-Induced Damage inInternational journal of molecular sciences · 2025Article
- Optimized LC-MS method for simultaneous polyamine profiling and ADC/ODC activity quantification and evidence that ADCs are indispensable for flower development in tomato.Frontiers in plant science · 2025Article
- Effects of different straw breeding substrates on the growth of tomato seedlings and transcriptome analysis.Scientific reports · 2024Article
- Spermidine Improves Freezing Tolerance by Regulating HAntioxidants (Basel, Switzerland) · 2024Article
- UV-B Radiation EnhancesPlants (Basel, Switzerland) · 2024Article
- Article
- OliveAtlas: A Gene Expression Atlas Tool forPlants (Basel, Switzerland) · 2023Article
- Interactions of Polyamines and Phytohormones in Plant Response to Abiotic Stress.Plants (Basel, Switzerland) · 2023Review
- Integrated Metabolomic and Transcriptomic Analysis Reveals That Amino Acid Biosynthesis May Determine Differences in Cold-Tolerant and Cold-Sensitive Tea Cultivars.International journal of molecular sciences · 2023Article
- Genome-Wide Identification and Characterization of the Polyamine Uptake Transporter (Put) Gene Family in Tomatoes and the Role of Put2 in Response to Salt Stress.Antioxidants (Basel, Switzerland) · 2023Article
- Spermine inhibits PAMP-induced ROS and Ca2+ burst and reshapes the transcriptional landscape of PAMP-triggered immunity in Arabidopsis.Journal of experimental botany · 2023Article
- A comparative transcriptomic analysis reveals a coordinated mechanism activated in response to cold acclimation in common vetch (Vicia sativa L.).BMC genomics · 2022Article
61 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The levels of endogenous polyamines have been shown to increase in plant cells challenged with low temperature; however, the functions of polyamines in the regulation of cold stress responses are unknown. Here, we show that the accumulation of putrescine under cold stress is essential for proper cold acclimation and survival at freezing temperatures because Arabidopsis (Arabidopsis thaliana) mutants defective in putrescine biosynthesis (adc1, adc2) display reduced freezing tolerance compared to wild-type plants. Genes ADC1 and ADC2 show different transcriptional profiles upon cold treatment; however, they show similar and redundant contributions to cold responses in terms of putrescine accumulation kinetics and freezing sensitivity. Our data also demonstrate that detrimental consequences of putrescine depletion during cold stress are due, at least in part, to alterations in the levels of abscisic acid (ABA). Reduced expression of NCED3, a key gene involved in ABA biosynthesis, and down-regulation of ABA-regulated genes are detected in both adc1 and adc2 mutant plants under cold stress. Complementation analysis of adc mutants with ABA and reciprocal complementation tests of the aba2-3 mutant with putrescine support the conclusion that putrescine controls the levels of ABA in response to low temperature by modulating ABA biosynthesis and gene expression.
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