Evidence map›Paper›PMID 18701663›Full record

ArticleJournal of clinical microbiology2008

Evaluation of methods for rapid detection of resistance to isoniazid and rifampin in Mycobacterium tuberculosis isolates collected in the Caribbean.

Patrick Eberechi Akpaka, Shirematee Baboolal, Denise Clarke, Lorraine Francis, Nalin Rastogi

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Molecular screening of multidrug-resistance tuberculosis by a designated public health laboratory in Taiwan.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017
    Article
  2. Diagnostic Performance of the GenoType MTBDRChinese medical journal · 2017
    Article
  3. Redefining MTBDRplus test results: what do indeterminate results actually mean?The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2016
    Article
  4. General and advanced diagnostic tools to detect Mycobacterium tuberculosis and their drug susceptibility: a review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
    Review
  5. Article
  6. Observational
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Patrick Eberechi AkpakaDepartment of Para-Clinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad & Tobago. Patrick.Akpaka@sta.uwi.edu
Shirematee Baboolal
Denise Clarke
Lorraine Francis
Nalin Rastogi
University of the Southern Caribbean · TTUniversity of the West Indies · TTInstitut Pasteur de la Guadeloupe · GP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid identification of drug-resistant strains of Mycobacterium tuberculosis is crucial for the timely initiation of appropriate antituberculosis therapy. The performance of the Genotype MTBDRplus assay was compared with that of the Bactec 460 TB system, a "gold standard" culture-based method. The Genotype MTBDRplus assay was quicker and more cost-effective for the detection of rifampin resistance, but it was not as good for the detection of isoniazid-resistant strains in our setting.

Indexed as

Drug Resistance, BacterialAntitubercular AgentsCaribbean RegionDNA, BacterialHumansIsoniazidMicrobial Sensitivity TestsMolecular Diagnostic TechniquesMycobacterium tuberculosisRifampinTime FactorsTuberculosisAntitubercular AgentsDNA, BacterialIsoniazidRifampin

Identifiers

PMID18701663
PMCPMC2566078
OpenAlexW2039076404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.