ArticleJournal of clinical microbiology2008
Inter- and intra-assay reproducibility of microplate Alamar blue assay results for isoniazid, rifampicin, ethambutol, streptomycin, ciprofloxacin, and capreomycin drug susceptibility testing of Mycobacterium tuberculosis.
Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Diagnostic accuracy and reproducibility of WHO-endorsed phenotypic drug susceptibility testing methods for first-line and second-line antituberculosis drugs.Journal of clinical microbiology · 2013Pooled it
- Article
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- Determining the effect of a new truncated CecropinA-Magenin2 (CE-MA) hybrid peptide on the expression of multidrug-resistant (MDR) Mycobacterium tuberculosis efflux genes.Archives of microbiology · 2025Article
- The importance of heteroresistance and efflux pumps in bedaquiline-resistant Mycobacterium tuberculosis isolates from Iran.Annals of clinical microbiology and antimicrobials · 2024Article
- Proficiency of phenotypic drug susceptibility testing for Mycobacterium tuberculosis in China, 2008-2021.PloS one · 2024Article
- Immunomodulatory Activity of Diterpenes over Innate Immunity and Cytokine Production in a Human Alveolar Epithelial Cell Line Infected withCurrent molecular pharmacology · 2023Article
- Identification of Mutations Associated With Macozinone-Resistant in Mycobacterium Tuberculosis.Current microbiology · 2022Article
- Detecting Ethambutol Resistance inFrontiers in microbiology · 2020Article
- Scrutinizing the drug resistance mechanism of multi- and extensively-drug resistantAntimicrobial resistance and infection control · 2019Article
- Mutations withinAntimicrobial agents and chemotherapy · 2018Article
- Screening of Fruits of Seven Plants Indicated for Medicinal Use in Iraq.Pharmacognosy magazine · 2017Article
- Susceptibility profiles of Nocardia spp. to antimicrobial and antituberculotic agents detected by a microplate Alamar Blue assay.Scientific reports · 2017Article
- PdtaS Deficiency Affects Resistance of Mycobacteria to Ribosome Targeting Antibiotics.Frontiers in microbiology · 2017Article
- Antimycobacterial activity of five efflux pump inhibitors against Mycobacterium tuberculosis clinical isolates.The Journal of antibiotics · 2016Article
- Rational design and synthesis of novel diphenyl ether derivatives as antitubercular agents.Drug design, development and therapy · 2016Article
- Study of efflux pump gene expression in rifampicin-monoresistant Mycobacterium tuberculosis clinical isolates.The Journal of antibiotics · 2015Article
- Efflux pump gene expression in multidrug-resistant Mycobacterium tuberculosis clinical isolates.PloS one · 2015Article
- Measuring of Mycobacterium tuberculosis growth. A correlation of the optical measurements with colony forming units.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2013Article
- Antimicrobial susceptibility of standard strains of nontuberculous mycobacteria by microplate Alamar Blue assay.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
The intersample and intrasample variability of the results obtained with the microplate Alamar blue assay for the indirect drug susceptibility testing of Mycobacterium tuberculosis was investigated. Between 1.2 and 8.5% of paired MICs differed by more than one twofold dilution, resulting in discordant susceptible-resistant designations at frequencies between 0.6% (rifampin) and 18.9% (ethambutol).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.