ReviewAmerican journal of physiology. Renal physiology2008
A lipid-protein hybrid model for tight junction.
Review in American journal of physiology. Renal physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Article
- Cell death and barrier disruption by clinically used iodine concentrations.Life science alliance · 2023Article
- The Epithelial Cell Leak Pathway.International journal of molecular sciences · 2021Review
- Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function.Scientific reports · 2021Article
- Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies.Trends in molecular medicine · 2021Review
- Assessment of the cellular localisation of the annexin A2/S100A10 complex in human placenta.Journal of molecular histology · 2018Article
- The ancient claudin Dni2 facilitates yeast cell fusion by compartmentalizing Dni1 into a membrane subdomain.Cellular and molecular life sciences : CMLS · 2018Article
- Roles of membrane lipids in the organization of epithelial cells: Old and new problems.Tissue barriers · 2018Review
- Increased catabolism and decreased unsaturation of ganglioside in patients with inflammatory bowel disease.World journal of gastroenterology · 2015Observational
- Conceptual barriers to understanding physical barriers.Seminars in cell & developmental biology · 2015Review
- Annexin A2 complexes with S100 proteins: structure, function and pharmacological manipulation.British journal of pharmacology · 2015Review
- Barriers to the free diffusion of proteins and lipids in the plasma membrane.The Journal of cell biology · 2015Review
- "You Shall Not Pass"-tight junctions of the blood brain barrier.Frontiers in neuroscience · 2014Review
- A human claudin-1-derived peptide inhibits hepatitis C virus entry.Hepatology (Baltimore, Md.) · 2012Article
- Functions of lipid raft membrane microdomains at the blood-brain barrier.Journal of molecular medicine (Berlin, Germany) · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The epithelial tight junction (TJ) was first described ultrastructurally as a fusion of the outer lipid leaflets of the adjoining cell membrane bilayers (hemifusion). The discovery of an increasing number of integral TJ and TJ-associated proteins has eclipsed the original lipid-based model with the wide acceptance of a protein-centric model for the TJ. In this review, we stress the importance of lipids in TJ structure and function. A lipid-protein hybrid model accommodates a large body of information supporting the lipidic characteristics of the TJ, harmonizes with the accumulating evidence supporting the TJ as an assembly of lipid rafts, and focuses on an important, but relatively unexplored, field of lipid-protein interactions in the morphology, physiology, and pathophysiology of the TJ.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.