ReviewCanadian family physician Medecin de famille canadien2008
Acute otitis media in children with tympanostomy tubes.
Review in Canadian family physician Medecin de famille canadien, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03655665 (Does the Use of Topical Otic Drops at the Time of Tympanostomy Tube Placement Improve Outcomes When no Middle Ear Effusion is Present at the Time of Surgery), which is not on this map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Does the Use of Topical Otic Drops at the Time of Tympanostomy Tube Placement Improve Outcomes When no Middle Ear Effusion is Present at the Time of Surgery
Who cites it
5 citing papers in PubMed, 15 citations in OpenAlex.
- Novel Antimicrobial Treatment Strategy Based on Drug Delivery Systems for Acute Otitis Media.Frontiers in pharmacology · 2021Review
- An extended release ciprofloxacin/dexamethasone hydrogel for otitis media.International journal of pediatric otorhinolaryngology · 2020Article
- Treatment of otitis media by transtympanic delivery of antibiotics.Science translational medicine · 2016Article
- Beta- lactam antibiotics stimulate biofilm formation in non-typeable haemophilus influenzae by up-regulating carbohydrate metabolism.PloS one · 2014Article
- Full disclosure.Canadian family physician Medecin de famille canadien · 2008Article
Corrections and comments
- Commented on byFull disclosure.2008
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo review evidence regarding antibiotic treatment of acute otitis media in children with tympanostomy tubes and to discuss antibiotic resistance and ototoxicity. QUALITY OF EVIDENCE: MEDLINE, EMBASE, the Cochrane Database of Systematic Reviews, and the Cochrane Central Register of Controlled Trials were searched for relevant articles. Articles providing level I evidence(randomized controlled trials) for treatment were used. Key words used in the search included otitis media(MeSH), middle ear ventilation (MeSH), tympanostomy tubes, and otorrhea. MAIN MESSAGE: Tympanostomy tube insertion is a common procedure; acute otitis media is a frequent sequela. Treatment options include systemic or topical antibiotics with or without corticosteroids. The development of bacterial resistance to antibiotics and ototoxicity related to treatment are important considerations. There have been well-conducted randomized controlled trials of topical versus systemic antibiotic agents. Combined with proper ear cleaning and tragal pumping, topical fluoroquinolone agents offer the most effective treatment.
conclusionCurrent evidence suggests that a topical fluoroquinolone, with or without a corticosteroid, is the treatment of choice for acute otitis media with tympanostomy tubes.
Indexed as
Identifiers
18697973PMC2515237W2114149331What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.