ArticleCell stress & chaperones2009
Extreme thermotolerance and behavioral induction of 70-kDa heat shock proteins and their encoding genes in honey bees.
Article in Cell stress & chaperones, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 76 citations in OpenAlex.
- Integrated Assessment of Pollen Substitute Diets in Honey Bees Based on Transcriptional Responses, Immune-Derived Predicted Biological Age, and Survival.Animals : an open access journal from MDPI · 2026Article
- A Wireless Sensor Platform for Beehive Monitoring.Sensors (Basel, Switzerland) · 2026Article
- Article
- Climate change-induced stress in the honey beeFrontiers in physiology · 2025Review
- Based proteomics analyses reveal response mechanisms of Apis mellifera (Hymenoptera: Apidae) against the heat stress.Journal of insect science (Online) · 2024Article
- Article
- Proteomic differences in seminal fluid of social insects whose sperm differ in heat tolerance.Royal Society open science · 2023Article
- Expression Levels of Heat-Shock Proteins inInsects · 2023Article
- Linking Histone Methylation States andInsects · 2023Article
- Honeybees (Hymenoptera: Apidae) Adapt to the Shock of High Temperature and High Humidity Through Changes in Sugars and Polyols and Free Amino Acids.Journal of insect science (Online) · 2023Article
- Article
- Reproductive potential does not cause loss of heat shock response performance in honey bees.Scientific reports · 2020Article
- Article
- Expression of heat shock proteins in adult honey bee (Saudi journal of biological sciences · 2019Article
- Differential expression of acetylcholinesterase 1 in response to various stress factors in honey bee workers.Scientific reports · 2019Article
- Tolerance and response of two honeybee species Apis cerana and Apis mellifera to high temperature and relative humidity.PloS one · 2019Article
- RNA-Seq analysis of Polyrhachis vicina Roger and insights into the heat shock protein 90 and 70 families.Cell stress & chaperones · 2019Article
- Molecular chaperoning helps safeguarding mitochondrial integrity and motor functions in the Sahara silver ant Cataglyphis bombycina.Scientific reports · 2018Article
- The Wisdom of Honeybee Defenses Against Environmental Stresses.Frontiers in microbiology · 2018Review
- The heat shock response and humoral immune response are mutually antagonistic in honey bees.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Foraging honey bees frequently leave the hive to gather pollen and nectar for the colony. This period of their lives is marked by periodic extremes of body temperature, metabolic expenditure, and flight muscle activity. Following ecologically relevant episodes of hyperthermia between 33 degrees C and 50 degrees C, heat shock protein 70 (Hsp70) expression and hsp70/hsc70-4 activity in brains of nonflying laboratory-held bees increased by only two to three times baseline at temperatures 46-50 degrees C. Induction was undetectable in thoracic-flight muscles. Yet, thorax hsp70 mRNA (but not hsc70-4 mRNA) levels were up to ten times higher in flight-capable hive bees and foraging bees compared to 1-day-old, flight-incapable bees, while brain hsp70/hsc70-4 mRNA levels were low and varied little among behavioral groups. These data suggest honey bee tissues, especially flight muscles, are extremely thermotolerant. Furthermore, Hsp70 expression in the thoraces of flight-capable bees is probably flight-induced by oxidative and mechanical damage to flight muscle proteins rather than temperature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.