ArticleEuropean journal of clinical pharmacology2008
A clinical evaluation of the Janus Web Application, a software screening tool for drug-drug interactions.
Article in European journal of clinical pharmacology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Nurse-led medication reviews and the quality of drug treatment of elderly hospitalized patients.European journal of clinical pharmacology · 2009Trial
- Employing bibliometrics and natural language processing (NLP) to analyse real-world applications of adverse drug reaction.Exploratory research in clinical and social pharmacy · 2025Article
- Evaluating EHR-Integrated Digital Technologies for Medication-Related Outcomes and Health Equity in Hospitalised Adults: A Scoping Review.Journal of medical systems · 2024Article
- Adherence to guidelines for avoiding drug interactions associated with warfarin--a Nationwide Swedish Register Study.PloS one · 2014Article
- Adherence to drug label recommendations for avoiding drug interactions causing statin-induced myopathy--a nationwide register study.PloS one · 2013Article
- The incidence of potential drug-drug interactions in elderly patients with arterial hypertension.Pharmacy world & science : PWS · 2010Article
- Nationwide drug-dispensing data reveal important differences in adherence to drug label recommendations on CYP2D6-dependent drug interactions.British journal of clinical pharmacology · 2010Article
- Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the clinical relevance of the Janus Web Application (JWA) in screening for potential drug-drug interactions (DDIs).
methodsOne hundred and fifty patients taking two drugs or more were studied. Potential DDIs were identified by the JWA. Interviewing the patient and looking into his/her medical records provided complementing information. A clinical pharmacologist judged which potential DDIs were clinically relevant. Potentially relevant DDIs identified by the JWA were then correlated with clinically relevant DDIs.
resultsA total of 150 significant potential DDIs were found. Sixteen percent (24/150) were judged to be clinically relevant.
conclusionsA very small proportion of DDIs was considered clinically relevant in the specific clinical context. To optimise the software's user-friendliness, the following points need to be considered: the possibility of eliminating trivial potential DDIs, individualising drug alerts, and providing written information, accessible via a hyperlink.
Indexed as
Identifiers
18695980What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.