Evidence map›Paper›PMID 18695979›Full record

ArticleEuropean journal of clinical pharmacology2008

Patient educational level and use of newly marketed drugs: a register-based study of over 600,000 older people.

Syed Imran Haider, Kristina Johnell, Gunilla Ringbäck Weitoft, Mats Thorslund, Johan Fastbom

Abstract read
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In one paragraph

Article in European journal of clinical pharmacology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Socioeconomic status, antidepressant use, and return to work after disability due to common mental disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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  8. Review
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  10. Educational level and use of osteoporosis drugs in elderly men and women: a Swedish nationwide register-based study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
    Article
  11. Personalized therapeutics: a potential threat to health equity.Journal of general internal medicine · 2012
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Syed Imran HaiderAging Research Center, Karolinska Institutet, Gävlegatan 16, 11330 Stockholm, Sweden. Imran.Haider@ki.se
Kristina Johnell
Gunilla Ringbäck Weitoft
Mats Thorslund
Johan Fastbom
Karolinska Institutet · SENational Board of Health and Welfare · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the association between educational level and the use of newly marketed drugs (NMD) among elderly persons.

methodsWe conducted a register-based, retrospective, cross-sectional study of 626,258 people aged 75-89 years who filled at least one drug prescription from August to October 2005 and who, consequently, were registered in the Swedish Prescribed Drug Register (SPDR). Data from the SPDR were record-linked to the Swedish National Inpatient Register and the Education Register. Newly marketed drugs were defined as new chemical entities that had been approved in Sweden between 2000 and 2004.

resultsOverall, NMD were prescribed to 7.3% of the study population. The use of NMD increased with increasing educational level (6.9% for the lowest educated elderly and 8.1% for the highest educated elderly), and education was associated with NMD [odds ratio (OR) 0.82; 95% confidence interval (CI)] 0.80-0.88 for <9 compared with > or =13 years of education) after adjustment for age, sex, type of residential area and number of dispensed drugs. Decreasing educational level was associated with a lower probability of using most of the NMD, especially oseltamivir (adjusted OR 0.16; 95% CI 0.12-0.22 for <9 years of education compared with > or =13 years of education) and ezetimibe.

conclusionsThis study suggests that education-related inequalities in NMD use may exist even in a healthcare system that claims to ensure a high degree of equity. Future research is required to explain why educational level influences the selection of new drugs and whether it has any impact on health outcomes.

Indexed as

Drug Utilization ReviewPatient Education as TopicPrescription DrugsRegistriesAgedCross-Sectional StudiesHealth Knowledge, Attitudes, PracticeHumansMarketing of Health ServicesRetrospective StudiesSocioeconomic FactorsSwedenPrescription Drugs

Identifiers

PMID18695979
OpenAlexW2085710833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.