ArticleInternational journal of oncology2008
The expression ratio of Map7/B2M is prognostic for survival in patients with stage II colon cancer.
Article in International journal of oncology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A structural and dynamic visualization of the interaction between MAP7 and microtubules.Nature communications · 2024Article
- Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase.iScience · 2023Article
- Clinical Significance of MAP-7 and FOXC1 in Egyptian Acute Myeloid Leukemia Patients.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Key Markers Involved in the Anticolon Cancer Response of CD8+ T Cells through the Regulation of Cholesterol Metabolism.Journal of oncology · 2021Article
- Enhanced expression of microtubule-associated protein 7 functioned as a contributor to cervical cancer cell migration and is predictive of adverse prognosis.Cancer cell international · 2020Article
- Identification of a five-mRNA signature as a novel potential prognostic biomarker in pediatric Wilms tumor.Molecular genetics & genomic medicine · 2020Article
- MAP7 promotes migration and invasion and progression of human cervical cancer through modulating the autophagy.Cancer cell international · 2020Article
- Data-independent acquisition of the proteomics of spleens from chickens infected by avian leukosis virus.3 Biotech · 2019Article
- TheThe Journal of cell biology · 2019Article
- Identifying autophagy gene-associated module biomarkers through construction and analysis of an autophagy-mediated ceRNA‑ceRNA interaction network in colorectal cancer.International journal of oncology · 2018Article
- Identification of Potential Key Genes Associated With the Pathogenesis and Prognosis of Gastric Cancer Based on Integrated Bioinformatics Analysis.Frontiers in genetics · 2018Article
- High expression of MAP7 predicts adverse prognosis in young patients with cytogenetically normal acute myeloid leukemia.Scientific reports · 2016Article
- Data on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations.Data in brief · 2016Article
- A Decision Tree Based Classifier to Analyze Human Ovarian Cancer cDNA Microarray Datasets.Journal of medical systems · 2016Article
- The identification of novel targets of miR-16 and characterization of their biological functions in cancer cells.Molecular cancer · 2013Article
- Highly synergistic effect of sequential treatment with epigenetic and anticancer drugs to overcome drug resistance in breast cancer cells is mediated via activation of p21 gene expression leading to G2/M cycle arrest.Molecular pharmaceutics · 2013Article
- Temporal genomewide expression profiling of DSS colitis reveals novel inflammatory and angiogenesis genes similar to ulcerative colitis.Physiological genomics · 2011Article
- beta(2)microglobulin mRNA expression levels are prognostic for lymph node metastasis in colorectal cancer patients.British journal of cancer · 2008Article
- Immunoprofiles of colorectal cancer from Lynch syndrome.OncoimmunologyArticle
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Colorectal cancer (CRC) is the second most frequent cause of cancer-related death in the United States. To determine whether certain molecular markers might be prognostic for survival, we measured by quantitative real-time RT-PCR the expression levels of 15 previously studied genes that are known to be up-regulated or down-regulated in the progression of epithelial cancers. The tumor samples were extracted from formalin-fixed paraffin-embedded primary tissues derived from patients with Stage II CRC who developed disease recurrence within two years (n=10), or were disease-free for at least 4 years (n=12). We were able to determine, by AUC curve analysis, that the ratio of microtubule associated protein 7 (Map7)/B2M was predictive of outcome in our sample set. Further, using Kaplan-Meier survival analysis, we observed significantly different curves as a function of marker positivity for the Map7/B2M (p=0.0001; HR=11) expression ratio. This suggests that the expression ratio of Map7/B2M may serve as a valuable prognostic marker in patients with Stage II colon cancer, and potentially guide therapeutic decision making.
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18695889PMC3399116What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.