ReviewCurrent drug safety2008
Lead encephalopathy due to traditional medicines.
Review in Current drug safety, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.
- Lead and arsenic intoxications by traditional and alternative medicine: men are more sensitive than women.Naunyn-Schmiedeberg's archives of pharmacology · 2025Pooled it
- Lactobacillus protects against lead-induced hepatotoxicity by preserving the gut barrier and microbiota remodeling.BMC microbiology · 2026Article
- Reducing lead toxicity with advanced nanotechnology methods.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Unmasking herbal medication-induced lead poisoning in a geriatric patient with gastrointestinal symptoms.BMJ case reports · 2023Article
- Article
- Environmental and health risks of perovskite solar modules: Case for better test standards and risk mitigation solutions.iScience · 2023Review
- Health Remedies as a Source of Lead, Mercury, and Arsenic Exposure, New York City, 2010-2019.American journal of public health · 2022Article
- Mechanisms associated with the dysregulation of mitochondrial function due to lead exposure and possible implications on the development of Alzheimer's disease.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022Review
- Multivariate statistical evaluation of heavy metals in the urine of opium individuals in comparison with healthy people in Western Iran.Environmental science and pollution research international · 2022Article
- Heavy Metals in Acrylic Color Paints Intended for the School Children Use: A Potential Threat to the Children of Early Age.Molecules (Basel, Switzerland) · 2021Article
- Unusual Domestic Source of Lead Poisoning.International journal of environmental research and public health · 2020Article
- Cholesterol and Oxidative Stress in U.S. Pregnant Women Exposed to Lead.Medical sciences (Basel, Switzerland) · 2019Article
- Lead: Tiny but Mighty Poison.Indian journal of clinical biochemistry : IJCB · 2018Review
- Opium addiction as new source of lead poisoning: An emerging epidemic in Iran.EXCLI journal · 2018Article
- Toxicants in folk remedies: implications of elevated blood lead in an American-born infant due to imported diaper powder.Environmental geochemistry and health · 2017Article
- Whole Medical Systems versus the System of Conventional Biomedicine: A Critical, Narrative Review of Similarities, Differences, and Factors That Promote the Integration Process.Evidence-based complementary and alternative medicine : eCAM · 2017Review
- Lead Poisoning Can Be Easily Misdiagnosed as Acute Porphyria and Nonspecific Abdominal Pain.Case reports in emergency medicine · 2017Article
- Effects of Lead in Various Preparatory Stages ofJournal of clinical and diagnostic research : JCDR · 2016Article
- Lead toxicity: a review.Interdisciplinary toxicology · 2015Review
- A cluster of lead poisoning among consumers of Ayurvedic medicine.International journal of occupational and environmental health · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Traditional medicine use is common in developing countries and increasingly popular in the western world. Despite the popularity of traditional medicines, scientific research on safety and efficacy is limited. However documented fatalities and severe illness due to lead poisoning are increasingly recognized to be associated with traditional medicine use. As society becomes more globalized, it is imperative for pharmacists and health care providers to learn about the safety of traditional medical practices. The information presented educates and alerts pharmacists and health care providers about the potential of traditional medicines to cause lead encephalopathy. Case reports were located through systematic literature searches using MEDLINE, CINAHL, AMED, CISCOM, EMBASE and The Cochrane library from 1966 to the February 2007. Reference lists of identified articles and the authors' own files were also searched. Inclusion criteria were cases of human lead encephalopathy associated with traditional medical practices. There were no restrictions regarding the language of publication. Data were subsequently extracted and summarized in narrative and tabular form. We found 76 cases of lead encephalopathy potentially associated with traditional medicine. Ayurvedic medicines were associated with 5 cases (7%), Middle eastern traditional medicines with 66 cases (87%) and 5 cases (7%) with other traditional medicines. Of the 76 cases, 5% were in adults and 95% were in infants and young children. Of the 4 adult cases, at least one was left with residual neurological impairment. In infants and young children, among 72 cases 8 (11%) were fatal, and at least 15 (21%) had residual neurological deficits. Traditional medicine users should be screened for lead exposure and strongly encouraged to discontinue metal-containing remedies. Therefore, the United States Food and Drug Administration and corresponding agencies in other countries should require and enforce heavy metal testing for all imported traditional medicines and "dietary supplements".
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.