ReviewWorld journal of urology2008
Does mechanical stimulation have any role in urinary bladder tissue engineering?
Review in World journal of urology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Current evidence regarding alternative techniques for enterocystoplasty using regenerative medicine methods: a systematic review.European journal of medical research · 2024Pooled it
- Review of clinical experience on biomaterials and tissue engineering of urinary bladder.World journal of urology · 2020Pooled it
- [Biological function of bladder smooth muscle cells regulated by multi-modal biomimetic stress].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024Article
- Tissue Engineering and Regenerative Medicine in Pediatric Urology: Urethral and Urinary Bladder Reconstruction.International journal of molecular sciences · 2022Review
- Electrospinning: Application and Prospects for Urologic Tissue Engineering.Frontiers in bioengineering and biotechnology · 2020Review
- Stretchable collagen-coated polyurethane-urea hydrogel seeded with bladder smooth muscle cells for urethral defect repair in a rabbit model.Journal of materials science. Materials in medicine · 2019Article
- Bioengineering Approaches for Bladder Regeneration.International journal of molecular sciences · 2018Review
- Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder.Nature reviews. Urology · 2018Review
- The effect of a cyclic uniaxial strain on urinary bladder cells.World journal of urology · 2017Article
- Organ-specific matrix self-assembled by mesenchymal cells improves the normal urothelial differentiation in vitro.World journal of urology · 2016Article
- Endogenous Optical Signals Reveal Changes of Elastin and Collagen Organization During Differentiation of Mouse Embryonic Stem Cells.Tissue engineering. Part C, Methods · 2015Article
- Tissue-engineered urinary conduits.Current urology reports · 2015Review
- Regenerative medicine as applied to general surgery.Annals of surgery · 2012Review
- Regenerative medicine strategies for treating neurogenic bladder.International neurourology journal · 2011Article
- Generating elastin-rich small intestinal submucosa-based smooth muscle constructs utilizing exogenous growth factors and cyclic mechanical stimulation.Tissue engineering. Part A · 2009Article
- The bladder extracellular matrix. Part II: regenerative applications.Nature reviews. Urology · 2009Review
- Recent advances in urologic tissue engineering.Current urology reports · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTissue engineering of the urinary bladder currently relies on biocompatible scaffolds that deliver biological and physical functionality with negligible risks of immunogenic or tumorigenic potential. Recent research suggests that autologous cells that are propagated in culture and seeded on scaffolds prior to implantation improve clinical outcomes. For example, normal urinary bladder development in utero requires regular filling and emptying, and current research suggests that bladders constructed in vitro may also benefit from regular mechanical stimulation. Such stimulation appears to induce favorable cellular changes, proliferation, and production of structurally suitable extracellular matrix (ECM) components essential for the normal function of hollow dynamic organs. MATERIALS AND
methodsTo mimic in vivo urinary bladder dynamics, tissue bioreactors that imitate the filling and emptying of a normal bladder have been devised. A "urinary bladder tissue bioreactor" that is able to recapitulate these dynamics while providing a cellular environment that facilitates cell-cell and cell-matrix interactions normally seen in-vivo may be necessary to successfully engineer bladder tissue.
conclusionsThe validation of a urinary bladder tissue bioreactor that permits careful control of physiological conditions will generate a broad interest from researchers interested in urinary bladder physiology and tissue engineering.
Indexed as
Identifiers
18690457What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.