ArticleGenetics2008
Population bottlenecks increase additive genetic variance but do not break a selection limit in rain forest Drosophila.
Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 69 citations in OpenAlex.
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- The other 96%: Can neglected sources of fitness variation offer new insights into adaptation to global change?Evolutionary applications · 2017Article
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- Cryptic genetic variation: evolution's hidden substrate.Nature reviews. Genetics · 2014Review
- A classical genetic solution to enhance the biosynthesis of anticancer phytochemicals in Andrographis paniculata Nees.PloS one · 2014Article
- High genetic diversity is not essential for successful introduction.Ecology and evolution · 2013Article
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- The consequences of rare sexual reproduction by means of selfing in an otherwise clonally reproducing species.Theoretical population biology · 2011Article
- Slow inbred lines of Drosophila melanogaster express as much inbreeding depression as fast inbred lines under semi-natural conditions.Genetica · 2011Article
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- Elastic, not plastic species: frozen plasticity theory and the origin of adaptive evolution in sexually reproducing organisms.Biology direct · 2010Article
- Testing evolutionary hypotheses about species borders: patterns of genetic variation towards the southern borders of two rainforest Drosophila and a related habitat generalist.Proceedings. Biological sciences · 2009Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
According to neutral quantitative genetic theory, population bottlenecks are expected to decrease standing levels of additive genetic variance of quantitative traits. However, some empirical and theoretical results suggest that, if nonadditive genetic effects influence the trait, bottlenecks may actually increase additive genetic variance. This has been an important issue in conservation genetics where it has been suggested that small population size might actually experience an increase rather than a decrease in the rate of adaptation. Here we test if bottlenecks can break a selection limit for desiccation resistance in the rain forest-restricted fly Drosophila bunnanda. After one generation of single-pair mating, additive genetic variance for desiccation resistance increased to a significant level, on average higher than for the control lines. Line crosses revealed that both dominance and epistatic effects were responsible for the divergence in desiccation resistance between the original control and a bottlenecked line exhibiting increased additive genetic variance for desiccation resistance. However, when bottlenecked lines were selected for increased desiccation resistance, there was only a small shift in resistance, much less than predicted by the released additive genetic variance. The small selection response in the bottlenecked lines was no greater than that observed in the control lines. Thus bottlenecks might produce a statistically detectable change in additive genetic variance but this change has no impact on the response to selection.
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