ArticleThe American journal of tropical medicine and hygiene2008
Evolutionary origins, diversification, and biogeography of liver flukes (Digenea, Fasciolidae).
Article in The American journal of tropical medicine and hygiene, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 98 citations in OpenAlex.
- Hepatic Morphological Lesions and Blood Biochemical Evidence of Impaired Metabolism in Wild European Moose (Veterinary medicine international · 2026Article
- Intermediate host recognition abilities of Fasciola hepatica miracidia.Parasites & vectors · 2025Article
- Genetic diversity and population structure of Fasciola gigantica isolated from cattle in Malawi.Veterinary research communications · 2025Article
- Seasonal dynamics and molecular phylogenetic studies on cercariae in Central Zone of Kashmir valley.PloS one · 2025Article
- Histopathological Lesions Caused by a Digenean Trematode in a Pest Apple Snail,Animals : an open access journal from MDPI · 2024Article
- Trematode Genomics and Proteomics.Advances in experimental medicine and biology · 2024Article
- A proposed ectochory ofInternational journal for parasitology. Parasites and wildlife · 2023Article
- Fasciolosis: pathogenesis, host-parasite interactions, and implication in vaccine development.Frontiers in veterinary science · 2023Review
- Molecular characterization ofFrontiers in veterinary science · 2023Article
- Potential Hybridization ofPathogens (Basel, Switzerland) · 2022Article
- Phylogenomics and Diversification of the Schistosomatidae Based on Targeted Sequence Capture of Ultra-Conserved Elements.Pathogens (Basel, Switzerland) · 2022Article
- New Insights Into the Genetic Variability ofHelminthologia · 2022Article
- Liver Fluke Infection Throughout Human Evolution.Gastro hep advances · 2022Review
- The spreading of parasites by human migratory activities.Virulence · 2020Review
- Article
- Adaptive Radiation of the Flukes of the Family Fasciolidae Inferred from Genome-Wide Comparisons of Key Species.Molecular biology and evolution · 2020Article
- New insight into genetic variation and haplotype diversity of Fasciola hepatica from Algeria.Parasitology research · 2019Article
- Updated molecular phylogenetic data for Opisthorchis spp. (Trematoda: Opisthorchioidea) from ducks in Vietnam.Parasites & vectors · 2017Article
- Molecular characterisation of four echinostomes (Digenea: Echinostomatidae) from birds in New Zealand, with descriptions of Echinostoma novaezealandense n. sp. and Echinoparyphium poulini n. sp.Systematic parasitology · 2017Article
- Fasciolopsis buski (Digenea: Fasciolidae) from China and India may represent distinct taxa based on mitochondrial and nuclear ribosomal DNA sequences.Parasites & vectors · 2017Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
Fasciolid flukes are among the largest and best known digenetic trematodes and have considerable historical and veterinary significance. Fasciola hepatica is commonly implicated in causing disease in humans. The origins, patterns of diversification, and biogeography of fasciolids are all poorly known. We have undertaken a molecular phylogenetic study using 28S, internal transcribed spacer 1 and 2 (ITS-1 and ITS-2) of nuclear ribosomal DNA, and mitochondrial nicotinamide dehydrogenase subunit 1 (nad1) that included seven of the nine recognized species in the family. The fasciolids examined comprise a monophyletic group with the most basal species recovered from African elephants. We hypothesize fasciolids migrated from Africa to Eurasia, with secondary colonization of Africa. Fasciolids have been conservative in maintaining relatively large adult body size, but anatomical features of their digestive and reproductive systems are available. These flukes have been opportunistic, with respect to switching to new snail (planorbid to lymnaeid) and mammalian hosts and from intestinal to hepatic habitats within mammals.
Indexed as
Identifiers
18689632PMC2577557W2129378975What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.