Evidence map›Paper›PMID 18689626›Full record

ArticleThe American journal of tropical medicine and hygiene2008

Epidemiology of cryptosporidiosis in North American travelers to Mexico.

Parvathy Nair, Jamal A Mohamed, Herbert L DuPont, Jose Flores Figueroa, Lily G Carlin, Zhi-Dong Jiang, Jaime Belkind-Gerson, Francisco G Martinez-Sandoval, Pablo C Okhuysen

Open access · greenAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 34 citations in OpenAlex.

  1. Use of nanoparticles, a modern means of drug delivery, against cryptosporidiosis.Journal of advanced veterinary and animal research · 2023
    Review
  2. Rapid detection ofHeliyon · 2023
    Article
  3. Review
  4. Article
  5. Article
  6. Childhood cryptosporidiosis: a case report.Journal of parasitology research · 2010
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Parvathy NairThe University of Texas Health Science Center at Houston Medical School and School of Public Health, Houston, Texas, USA.
Jamal A Mohamed
Herbert L DuPont
Jose Flores Figueroa
Lily G Carlin
Zhi-Dong Jiang
Jaime Belkind-Gerson
Francisco G Martinez-Sandoval
Pablo C Okhuysen
Instituto Nacional de Salud Pública · MXUniversidad Autónoma de Guadalajara · MXSwedish Civil Contingencies Agency · SEThe University of Texas Health Science Center at Houston · US

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI FASIHA KANWAL · 2001 to 2026
$28.3M
U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Gene Polymorphisms Predisposing to Infectious DiarrheaR01AI054948 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI OKHUYSEN, PABLO C · 2003 to 2007
$1.6M
NCRR NIH HHS UL1 RR024148NIAID NIH HHS R01 AI054948NIAID NIH HHS R01 AI54948-01NIDDK NIH HHS DK56338NIDDK NIH HHS P30 DK056338PHS HHS ULIRR024148
6 · The paper itself

Abstract

We studied 1,179 North American travelers who visited Mexico from 2005 to 2007. Travelers' diarrhea (TD) was reported by 521 (44%) participants. Among subjects with TD, 218 cases were examined for cryptosporidiosis by polymerase chain reaction (PCR) and enzyme-linked immunoassays (ELISA). There were 14 (6%) cases of cryptosporidiosis and 141 cases (64%) of bacterial diarrhea. Compared with bacterial diarrhea, a longer stay in Mexico was a risk factor for cryptosporidiosis. Additionally, Cryptosporidium cases passed greater number of watery stools (P < 0.05), suffered more episodes of diarrhea (P < or = 0.05), and were more likely to experience tenesmus (P < or = 0.05) compared with bacterial causes of TD. ELISA detected seven (3%) cases of Cryptosporidium, whereas PCR identified an additional seven cases (6%). Speciation by 18SrRNA sequencing showed that 13 cases were caused by C. parvum and only 1 case was caused by C. hominis. ELISA showed a sensitivity of 50% and specificity of 100% compared with PCR.

Indexed as

TravelAdolescentAdultAnimalsCanadaCryptosporidiosisCryptosporidiumDiarrheaEnzyme-Linked Immunosorbent AssayHumansMexicoOdds RatioPolymerase Chain ReactionRisk FactorsSensitivity and SpecificityTime Factors

Identifiers

PMID18689626
PMCPMC2560987
OpenAlexW2112188177

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.