Evidence map›Paper›PMID 18689478›Full record

ArticleJournal of bacteriology2008

Role of the Campylobacter jejuni Cj1461 DNA methyltransferase in regulating virulence characteristics.

Joo-Sung Kim, Jiaqi Li, If H A Barnes, David A Baltzegar, Mohanasundari Pajaniappan, Thomas W Cullen, M Stephen Trent, Christopher M Burns, Stuart A Thompson

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Editorial:Frontiers in microbiology · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Comparative Methylome Analysis ofFrontiers in microbiology · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain-Barré syndrome.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Joo-Sung KimDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta, GA 30912, USA.
Jiaqi Li
If H A Barnes
David A Baltzegar
Mohanasundari Pajaniappan
Thomas W Cullen
M Stephen Trent
Christopher M Burns
Stuart A Thompson
Augusta University · US

Funding

MODIFICATION OF HELICOBACTER PYLORI LIPOPOLYSACCHARIDESR01AI064184 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI TRENT, MICHAEL STEPHEN · 2006 to 2015
$3.4M
The Outer Surface of Vibrio CholeraeR01AI076322 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI TRENT, MICHAEL STEPHEN · 2008 to 2017
$3.2M
Campylobacter jejuni outer membrane protein vaccineR01AI058284 · NIAID · MEDICAL COLLEGE OF GEORGIA (MCG) · PI THOMPSON, STUART A · 2004 to 2009
$1.9M
Campylobacter jejuni proteins induced at 37CR01AI055715 · NIAID · MEDICAL COLLEGE OF GEORGIA (MCG) · PI THOMPSON, STUART A · 2003 to 2007
$1.4M
Campylobacter jejuni DNA methylation and gene regulationR21AI061026 · NIAID · MEDICAL COLLEGE OF GEORGIA (MCG) · PI THOMPSON, STUART A · 2004 to 2004
$320k
NIAID NIH HHS AI055715NIAID NIH HHS AI058284NIAID NIH HHS AI061026NIAID NIH HHS R01 AI055715NIAID NIH HHS R01 AI058284NIAID NIH HHS R01 AI064184NIAID NIH HHS R01AI064184NIAID NIH HHS R01 AI076322NIAID NIH HHS R01AI076322NIAID NIH HHS R21 AI061026
6 · The paper itself

Abstract

Mutation of the cj1461 predicted methyltransferase gene reduced the motility of Campylobacter jejuni 81-176. Electron microscopy revealed that the mutant strain had flagella but with aberrant structure. The Deltacj1461 mutant was sevenfold more adherent to but 50-fold less invasive of INT-407 human epithelial cells than the wild type.

Indexed as

Bacterial ProteinsCampylobacter jejuniCell LineDNA Modification MethylasesFlagellaGenetic Complementation TestHumansMicroscopy, Electron, TransmissionModels, GeneticMutationVirulenceBacterial ProteinsDNA Modification Methylases

Identifiers

PMID18689478
PMCPMC2565991
OpenAlexW2167212889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.