ArticleNucleic acids research2008
Stringent promoter recognition and autoregulation by the group 3 sigma-factor SigF in the cyanobacterium Synechocystis sp. strain PCC 6803.
Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Type IV pilin regulation: a transcriptional overview.Critical reviews in microbiology · 2026Review
- A cyanobacterial sigma factor F controls biofilm-promoting genes through intra- and intercellular pathways.Biofilm · 2024Article
- Mutations Suppressing the Lack of Prepilin Peptidase Provide Insights Into the Maturation of the Major Pilin Protein in Cyanobacteria.Frontiers in microbiology · 2021Article
- The Role of the Cyanobacterial Type IV Pilus Machinery in Finding and Maintaining a Favourable Environment.Life (Basel, Switzerland) · 2020Review
- Recent Advances in Biological Functions of Thick Pili in the CyanobacteriumFrontiers in plant science · 2020Review
- Article
- Regulation ofEcoSal Plus · 2017Review
- Screening and genetic characterization of thermo-tolerant Synechocystis sp. PCC6803 strains created by adaptive evolution.BMC biotechnology · 2014Article
- The omega subunit of the RNA polymerase core directs transcription efficiency in cyanobacteria.Nucleic acids research · 2014Article
- The gene ssl3076 encodes a protein mediating the salt-induced expression of ggpS for the biosynthesis of the compatible solute glucosylglycerol in Synechocystis sp. strain PCC 6803.Journal of bacteriology · 2010Article
- Stress sensors and signal transducers in cyanobacteria.Sensors (Basel, Switzerland) · 2010Review
- Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition.Genes & development · 2009Article
- Simultaneous inactivation of sigma factors B and D interferes with light acclimation of the cyanobacterium Synechocystis sp. strain PCC 6803.Journal of bacteriology · 2009Article
- Sigma factors for cyanobacterial transcription.Gene regulation and systems biology · 2009Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cyanobacteirum Synechocystis sp. strain PCC 6803 possesses nine species of the sigma (sigma)-factor gene for RNA polymerase (RNAP). Here, we identify and characterize the novel-type promoter recognized by a group 3 sigma-factor, SigF. SigF autoregulates its own transcription and recognizes the promoter of pilA1 that acts in pilus formation and motility in PCC 6803. The pilA1 promoter (PpilA1-54) was recognized only by SigF and not by other sigma-factors in PCC 6803. No PpilA1-54 activity was observed in Escherichia coli cells that possess RpoF (sigma(28)) for fragellin and motility. Studies of in vitro transcription for PpilA1-54 identified the region from -39 to -7 including an AG-rich stretch and a core promoter with TAGGC (-32 region) and GGTAA (-12 region) as important for transcription. We also confirmed the unique PpilA1-54 architecture and further identified two novel promoters, recognized by SigF, for genes encoding periplasmic and phytochrome-like phototaxis proteins. These results and a phylogenetic analysis suggest that the PCC 6803 SigF is distinct from the E. coli RpoF or RpoD (sigma(70)) type and constitutes a novel eubacterial group 3 sigma-factor. We discuss a model case of stringent promoter recognition by SigF. Promoter types of PCC 6803 genes are also summarized.
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