ArticleThe Biochemical journal2008
Arfs and membrane lipids: sensing, generating and responding to membrane curvature.
Article in The Biochemical journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines.Oncotarget · 2023Article
- A novel combinatorial approach of quantitative microscopy and in silico modeling deciphers Arf1-dependent Golgi size regulation.The European physical journal. E, Soft matter · 2019Article
- The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion.Scientific reports · 2017Article
- 1-Carbon Cycle Metabolites Methylate Their Way to Fatty Liver.Trends in endocrinology and metabolism: TEM · 2017Review
- ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5.Molecular biology of the cell · 2012Article
- Myoblast fusion: lessons from flies and mice.Development (Cambridge, England) · 2012Review
- Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain.The Journal of biological chemistry · 2011Article
- Influenza virus assembly and budding.Virology · 2011Review
- ADP-ribosylation factor 6 regulates mammalian myoblast fusion through phospholipase D1 and phosphatidylinositol 4,5-bisphosphate signaling pathways.Molecular biology of the cell · 2010Article
- Influenza virus m2 ion channel protein is necessary for filamentous virion formation.Journal of virology · 2010Article
- Insights into the classification of small GTPases.Advances and applications in bioinformatics and chemistry : AABC · 2010Article
- Domain-driven morphogenesis of cellular membranes.Current biology : CB · 2009Review
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Arf family GTP-binding proteins function in the regulation of membrane-trafficking events and in the maintenance of organelle structure. They act at membrane surfaces to modify lipid composition and to recruit coat proteins for the generation of transport vesicles. Arfs associate with membranes through insertion of an N-terminal myristoyl moiety in conjunction with an adjacent amphipathic alpha-helix, which embeds in the lipid bilayer when Arf1 is GTP-bound. In this issue of the Biochemical Journal, Lundmark et al. report that myristoylated Arfs in the presence of GTP bind to and cause tubulation of liposomes, and that GTP exchange on to Arfs is more efficient in the presence of liposomes of smaller diameter (increased curvature). These findings suggest that Arf protein activation and membrane interaction may initiate membrane curvature that will be enhanced further by coat proteins during vesicle formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.