Trial reportMedicine and science in sports and exercise2008
Muscle injury after repeated bouts of voluntary and electrically stimulated exercise.
Trial report in Medicine and science in sports and exercise, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Minimal Evidence for a Secondary Loss of Strength After an Acute Muscle Injury: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2017Pooled it
- Chronic effects of superimposed electromyostimulation during cycling on aerobic and anaerobic capacity.European journal of applied physiology · 2017Trial
- Localization and quantification of intramuscular damage using statistical parametric mapping and skeletal muscle parcellation.Scientific reports · 2015Trial
- Acute effects of superimposed electromyostimulation during cycling on myokines and markers of muscle damage.Journal of musculoskeletal & neuronal interactions · 2015Trial
- Effect of two maximal isometric contractions on eccentric exercise-induced muscle damage of the elbow flexors.European journal of applied physiology · 2013Trial
- Comparison in eccentric exercise-induced muscle damage among four limb muscles.European journal of applied physiology · 2011Trial
- Less indication of muscle damage in the second than initial electrical muscle stimulation bout consisting of isometric contractions of the knee extensors.European journal of applied physiology · 2010Trial
- Kinetics of rectus femoris stiffness, architecture, and muscle damage biomarkers in response to deceleration intensity during repeated sprints.European journal of applied physiology · 2026Article
- The impact of muscle oxidative capacity on neuromuscular recovery after exercise-induced muscle damage.European journal of applied physiology · 2026Article
- Heterogenous quadriceps femoris inter-head but consistent intra-head rigidity changes after voluntary eccentric exercise-induced muscle damage.European journal of applied physiology · 2026Article
- Neuromuscular electrical stimulation producing low evoked force elicits the repeated bout effect on muscle damage markers of the elbow flexors.Sports medicine and health science · 2025Article
- Eccentric Muscle Contractions: Risks and Benefits.Frontiers in physiology · 2019Review
- Time Course and Association of Functional and Biochemical Markers in Severe Semitendinosus Damage Following Intensive Eccentric Leg Curls: Differences between and within Subjects.Frontiers in physiology · 2018Article
- IL-6, Antioxidant Capacity and Muscle Damage Markers Following High-Intensity Interval Training Protocols.Journal of human kinetics · 2017Article
- Article
- The increase in surface EMG could be a misleading measure of neural adaptation during the early gains in strength.European journal of applied physiology · 2014Article
- Time course of central and peripheral alterations after isometric neuromuscular electrical stimulation-induced muscle damage.PloS one · 2014Article
- Low-intensity eccentric contractions attenuate muscle damage induced by subsequent maximal eccentric exercise of the knee extensors in the elderly.European journal of applied physiology · 2013Article
- The spectral changes in EMG during a second bout eccentric contraction could be due to adaptation in muscle fibres themselves: a simulation study.European journal of applied physiology · 2012Article
- Muscle damage protection by low-intensity eccentric contractions remains for 2 weeks but not 3 weeks.European journal of applied physiology · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
unlabelledRepeated bouts of eccentric exercise reduce the amount of exercise-induced muscle injury. PURPOSE: This study sought to evaluate the importance of neural adaptations by comparing the repeated bout effect on muscle injury caused by voluntary and electrically stimulated eccentric exercise.
methodsSixteen subjects (nine men, seven women) were assigned into two groups; electrical stimulation (STIM) and voluntary (VOL). Each group performed 2 identical bouts of 80 eccentric contractions of the quadriceps femoris (QF) through a 90 degree arc at approximately 45 degrees x s(-1), separated by 7 wk. T2-weighted magnetic resonance images of the QF were obtained before and 3 d after each exercise bout. Injury was assessed by determining changes in T2 relaxation time and muscle volume 3 d after exercise, and changes in isometric force and ratings of soreness for 28 d after exercise.
resultsThe initial bout of exercise caused significant changes in T2 relaxation time, isometric force, and ratings of soreness in both STIM and VOL groups (P < 0.05). After the repeated bout, significantly smaller changes were noted in soreness ratings (P < 0.05), mean change in T2 (P<0.05), and percentage of the QF demonstrating an increase in T2 (P < 0.05) compared with the initial bout in both exercise groups.
conclusionsA repeated-bout effect was observed after electrically stimulated exercise, and the magnitude of the effect was similar to that observed with voluntary exercise. This suggests that the primary mechanism for the reduction in muscle injury after repeated exercise bouts is not related to changes in muscle recruitment and is potentially related to structural changes within the muscles.
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