ReviewCurrent opinion in supportive and palliative care2008
Hematopoietic niche and bone meet.
Review in Current opinion in supportive and palliative care, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Bone marrow microenvironment: roles and therapeutic implications in obesity-associated cancer.Trends in cancer · 2023Review
- Article
- In Vitro Models of Bone Marrow Remodelling and Immune Dysfunction in Space: Present State and Future Directions.Biomedicines · 2022Review
- Review
- Expression ofCell journal · 2017Article
- Article
- Maintenance of the functional integrity of mouse hematopoiesis by EED and promotion of leukemogenesis by EED haploinsufficiency.Scientific reports · 2016Article
- Obesity-driven disruption of haematopoiesis and the bone marrow niche.Nature reviews. Endocrinology · 2014Review
- Spleens of myelofibrosis patients contain malignant hematopoietic stem cells.The Journal of clinical investigation · 2012Article
- Identification of functional tissue-resident cardiac stem/progenitor cells in adult mouse.Cell biology international reports · 2012Article
- Bone marrow-derived HipOP cell population is markedly enriched in osteoprogenitors.International journal of molecular sciences · 2012Article
- The niche as a target for hematopoietic manipulation and regeneration.Tissue engineering. Part B, Reviews · 2011Review
- After the bomb drops: a new look at radiation-induced multiple organ dysfunction syndrome (MODS).International journal of radiation biology · 2011Article
- Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2011Article
- Osteoimmunology and osteoporosis.Arthritis research & therapy · 2011Review
- Neoplastic bone marrow niche: hematopoietic and mesenchymal stem cells.Cell journal · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purpose of reviewTo provide an overview of the hematopoietic stem cell (HSC) niche in the bone marrow. In addition to highlighting recent advances in the field, we will also discuss components of the niche that may contribute to the development of cancer, or cancer metastases to the bone. RECENT
findingsMuch progress has been very recently made in the understanding of the cellular and molecular interactions in the HSC microenvironment. These recent findings point out the extraordinary complexity of the HSC microenvironment. Emerging data also suggest convergence of signals important for HSC and for leukemia or metastatic disease support. SUMMARY: The HSC niche comprises complex interactions between multiple cell types and molecules requiring cell-cell signaling as well as local secretion. These components can be thought of as therapeutic targets not only for HSC expansion, but also to modify behavior of hematopoietic malignancies and cancer metastases to the bone.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.