Evidence map›Paper›PMID 18685298›Full record

ReviewCurrent opinion in organ transplantation2008

Accommodation in organ transplantation.

Raymond J Lynch, Jeffrey L Platt

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in organ transplantation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
  2. The Evolution of Immunosuppressive Therapy in Pig-to-Nonhuman Primate Organ Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  3. Characterization of ABH-subtype donor-specific antibodies in ABO-A-incompatible kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  4. Article
  5. Review
  6. Antibody-mediated rejection with detection ofEuropean heart journal. Case reports · 2020
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Heparan Sulfate Proteoglycan Metabolism and the Fate of Grafted Tissues.Advances in experimental medicine and biology · 2015
    Review
  13. Cryptic B cell response to renal transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2013
    Article
  14. The paradoxical functions of B cells and antibodies in transplantation.Journal of immunology (Baltimore, Md. : 1950) · 2013
    Review
  15. Donor specific antibodies after transplantation.Pediatric transplantation · 2011
    Review
  16. Novel functions of B cells in transplantation.Current opinion in organ transplantation · 2011
    Review
  17. Article
  18. Accommodation in renal transplantation: unanswered questions.Current opinion in organ transplantation · 2010
    Review
  19. Antibodies in transplantation.Discovery medicine · 2010
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Raymond J LynchDepartment of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Jeffrey L Platt
Environmental Research Institute of Michigan · USUniversity of Michigan–Ann Arbor · US

Funding

T cell responses and cardiac transplantation in infancyP01HL079067 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLATT, JEFFREY L · 2005 to 2009
$6.3M
Xenogeneic Natural Antibody Targets-Structure/FunctionR37HL052297 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PLATT, JEFFREY L · 2001 to 2010
$3.9M
XENOGENEIC NATURAL ANTIBODY TARGETS--STRUCTURE/FUNCTIONR01HL052297 · NHLBI · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI PLATT, JEFFREY L · 1993 to 2000
$319k
NHLBI NIH HHS HL52297NHLBI NIH HHS HL79067NHLBI NIH HHS P01 HL079067NHLBI NIH HHS R01 HL052297NHLBI NIH HHS R37 HL052297
6 · The paper itself

Abstract

purpose of reviewWe review recent insights into the mechanisms and prevalence of accommodation. Accommodation refers to an acquired resistance of an organ graft to humoral injury and rejection. RECENT

findingsAccommodation has been postulated to reflect changes in antibodies, control of complement and/or acquired resistance to injury by antibodies, complement or other factors. We discuss the importance of these mechanisms, highlighting new conclusions. SUMMARY: Accommodation may be a common, perhaps the most common, outcome of organ transplantation and, in some systems, a predictable outcome of organ xenotransplantation. Further understanding of how accommodation is induced and by what mechanisms it is manifest and maintained could have a profound impact on transplantation in general and perhaps on other fields.

Indexed as

Organ TransplantationTransplantation ImmunologyAntibodiesAntigensComplement System ProteinsHumansAntibodiesAntigensComplement System Proteins

Identifiers

PMID18685298
PMCPMC2726737
OpenAlexW2151838081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.